Results 191 to 200 of about 3,387,841 (331)

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

A novel anatomical integrated acetabular plate for acetabular fracture involving posterior wall/column: a biomechanical study. [PDF]

Front Bioeng Biotechnol
Pei X, Chen Y, Fang Z, Xiong Z, Chen J, Zheng Y, Wang T, Qian S, Chen L, Wang G, Qi J, Liu X.   +11 more
europepmc   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Ballistic Performance of 7A52/7A62 Aluminum Alloy Laminates: A Numerical Investigation of Configuration Effect. [PDF]

Materials (Basel)
Wang Q, Yin M, Zhou J, Liu X, Zhang H, Mei R, Chen Z, Cao Y, Wang Q, Cong F, Zhang Y.   +10 more
europepmc   +1 more source

Fracture Dynamics of Natural Rust and Location Accuracy of Corrosion on Tank Bottom Plate

, 2004
Masahiro Kanzawa, Hideo Cho, Mikio Takemoto   +2 more
openalex   +2 more sources

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Biomechanical assessment of ten fixation techniques after sagittal split ramus osteotomy for significant mandibular advancement. [PDF]

Med Oral Patol Oral Cir Bucal
Silva WS, Buchaim RL, Laskarides C, Oreadi D, Viswanath A, Costa BE, Pereira-Silva M, Filho OM, Ribeiro-Junior PD.   +8 more
europepmc   +1 more source

Fatigue. Fatigue Strength Improvement of Lap Joints of Thin Steel Plates for Automobile Use by Using Low Transformation Temperature Welding Material.

, 2001
Akihiko Ohta, Kazuyoshi Matsuoka, Ninh T. Nguyen, Yoshio Maeda, Naoyuki Suzuki   +4 more
openalex   +2 more sources

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Dynamic microdevice culture during bovine oocyte maturation decreases lipid accumulation and improve blastocyst cell numbers. [PDF]

Sci Rep
Vit FF, Sangalli JR, Fiorenza MF, de Almeida Saraiva HFR, Ferst JG, Perecin F, Meirelles FV, de la Torre LG, da Silveira JC.   +8 more
europepmc   +1 more source