Results 91 to 100 of about 1,611,164 (288)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Development path of MaaS platforms in China

Journal of Highway and Transportation Research and Development
As urbanization progresses, a novel urban transportation paradigm known as Mobility as a Service (MaaS) has emerged, addressing the principles of environmentally friendly travel and sustainable transport development.
Wenkai Zhan, Zhendong Xie, Zhiguo Dong, Jiehan Yu, Ji Zhao   +4 more
doaj   +1 more source

Building an IoT Platform Based on Service Containerisation. [PDF]

Sensors (Basel), 2021
Antunes M, Santiago AR, Manso S, Regateiro D, Barraca JP, Gomes D, Aguiar RL.   +6 more
europepmc   +1 more source

Applying semantic web services to enterprise web [PDF]

, 2008
Enterprise Web provides a convenient, extendable, integrated platform for information sharing and knowledge management. However, it still has many drawbacks due to complexity and increasing information glut, as well as the heterogeneity of the ...
Hu, Y, Sun, X, Wei, P, Yang, Q P
core  

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source

MEDAS: an open-source platform as a service to help break the walls between medicine and informatics. [PDF]

Neural Comput Appl, 2022
Zhang L, Li J, Li P, Lu X, Gong M, Shen P, Zhu G, Shah SA, Bennamoun M, Qian K, Schuller BW.   +10 more
europepmc   +1 more source

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source

Genetics Adviser: a protocol for a mixed-methods randomised controlled trial evaluating a digital platform for genetics service delivery. [PDF]

BMJ Open, 2022
Shickh S, Hirjikaka D, Clausen M, Kodida R, Mighton C, Reble E, Sam J, Panchal S, Aronson M, Graham T, Armel SR, Glogowski E, Elser C, Eisen A, Carroll JC, Shuman C, Seto E, Baxter NN, Scheer A, Shastri-Estrada S, Feldman G, Thorpe KE, Schrader KA, Lerner-Ellis J, Kim RH, Faghfoury H, Bombard Y.   +26 more
europepmc   +1 more source

Developing ecosystem service indicators: experiences and lessons learned from sub-global assessments and other initiatives [PDF]

, 2011
People depend upon ecosystems to supply a range of services necessary for their survival and well-being. Ecosystem service indicators are critical for knowing whether or not these essential services are being maintained and used in a sustainable manner ...
Armenteras, Dolors, Ash, Neville, Barano, Thomas, Beltrame, Coralie, Berg, Hakan, Bhagabati, Nirmal, Biala, Katarzyna, Birge, Traci, Bondarev, Alexander, Brown, Claire, Butchart, Stuart, Davidson, Nick, De Groot, Rudolf, Doswald, Natalie, Díaz, Sandra, Espaldon, Maria Victoria, Fuentes, Rodrigo, Garcia, Keisha, Ghate, Utkarsh, Girvan, Alexander, Goethals, Peter, Hadian, Oki, Höft, Robert, Koleff, Patricia, Kumar, Chetan, Larigauderie, Anne, Lasco, Rodel, Layke, Christian, Linstead, Conor, Luque Panadero, Victoria Eugenia, Mainka, Sue, Mapendembe, Abisha, Marcela, Mónica, Nybo, Signe, O'Farell, Patrick, Reyers, Belinda, Ricketts, Taylor, Ringold, Paul, Rodríguez Rodríguez, Davíd, Rosenthal, Amy, Sandlund, Odd Terje, Sarukhán, José, Scharlemann, Jorn, Schlatter, Christian, Simpson, Lucy, Stott, Andrew, Tierney, Megan, Tyrell, Tristan, UNEP-WCMC, -, Urquiza, Tania, Vackár, David, van Oudenhoven, Alexander, Viglizzo, Ernesto, Walpole, Matt, Watts, Jim, Williams, James, Yashina, Tatyana, Zandri, Edoardo   +57 more
core   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman, Asako Takanohashi, Joshua Y. Joung, Geraldine W. Liu, Kaley Arnold, Amy Pizzino, Walter Faig, Sarah Woidill, Sona Narula, Adeline L. Vanderver   +9 more
wiley   +1 more source