Results 41 to 50 of about 1,611,164 (288)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Model-driven performance evaluation for service engineering [PDF]
, 2007 Service engineering and service-oriented architecture as an integration and platform technology is a recent approach to software systems integration.
Boskovic, Marko +2 more
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
IEEE Access, 2019 Bonus computing is a new metacomputing form that takes advantage of free computing power from the public Cloud market. To maximize the value of free Cloud resources and facilitate dividing Bonus computing tasks, it would particularly be crucial to ...
Zheng Li, Xue Guo
doaj +1 more source
Architecture Design of Healthcare Software-as-a-Service Platform for Cloud-Based Clinical Decision Support Service [PDF]
Healthcare Informatics Research, 2015 ObjectivesTo design a cloud computing-based Healthcare Software-as-a-Service (SaaS) Platform (HSP) for delivering healthcare information services with low cost, high clinical value, and high usability.MethodsWe analyzed the architecture requirements of ...
Sungyoung Oh +10 more
doaj +1 more source
Data Trusts as a Service: Providing a platform for multi‐party data sharing
International Journal of Information Management Data Insights, 2022 The major setback for data sharing is that data producers (i.e., subjects) are not able to determine how their data is being used/misused by data collectors (custodians).
Richard K. Lomotey +2 more
doaj +1 more source
Towards a re-engineering method for web services architectures [PDF]
, 2004 Recent developments in Web technologies – in particular through the Web services framework – have greatly enhanced the flexible and interoperable implementation of service-oriented software architectures.
Barrett, Ronan, Pahl, Claus
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
A Scalable Benchmark as a Service Platform [PDF]
, 2013 Load testing has always been a crucial and expensive activity for software companies. Classical solutions are a real burden to setup statically and their cost are prohibitive in terms of human and hardware resources. Cloud computing brings new opportunities to stress application scalability as load testing solutions can be provided on demand by the ...
Alain Tchana +5 more
openaire +1 more source
Optical Network as a Service for Service Function Chaining across Datacenters [PDF]
, 2017 We present the SPN OS, a Network-as-a-Service orchestration platform for NFV/SDN integrated service provisioning across multiple datacenters over packet/optical networks.
Ikeuchi, Tadashi +5 more
core +1 more source