Results 41 to 50 of about 1,603,360 (267)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Model-driven performance evaluation for service engineering [PDF]

open access: yes, 2007
Service engineering and service-oriented architecture as an integration and platform technology is a recent approach to software systems integration.
Boskovic, Marko   +2 more
core  

Trusted Launch of Virtual Machine Instances in Public IaaS Environments [PDF]

open access: yes, 2013
Cloud computing and Infrastructure-as-a-Service (IaaS) are emerging and promising technologies, however their adoption is hampered by data security concerns. At the same time, Trusted Computing (TC) is experiencing an increasing interest as a security
Aslam, Mudassar   +3 more
core   +4 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Do Google App Engine’s Runtimes Perform Homogeneously? An Empirical Investigation for Bonus Computing

open access: yesIEEE Access, 2019
Bonus computing is a new metacomputing form that takes advantage of free computing power from the public Cloud market. To maximize the value of free Cloud resources and facilitate dividing Bonus computing tasks, it would particularly be crucial to ...
Zheng Li, Xue Guo
doaj   +1 more source

Architecture Design of Healthcare Software-as-a-Service Platform for Cloud-Based Clinical Decision Support Service [PDF]

open access: yesHealthcare Informatics Research, 2015
ObjectivesTo design a cloud computing-based Healthcare Software-as-a-Service (SaaS) Platform (HSP) for delivering healthcare information services with low cost, high clinical value, and high usability.MethodsWe analyzed the architecture requirements of ...
Sungyoung Oh   +10 more
doaj   +1 more source

Data Trusts as a Service: Providing a platform for multi‐party data sharing

open access: yesInternational Journal of Information Management Data Insights, 2022
The major setback for data sharing is that data producers (i.e., subjects) are not able to determine how their data is being used/misused by data collectors (custodians).
Richard K. Lomotey   +2 more
doaj   +1 more source

Optical Network as a Service for Service Function Chaining across Datacenters [PDF]

open access: yes, 2017
We present the SPN OS, a Network-as-a-Service orchestration platform for NFV/SDN integrated service provisioning across multiple datacenters over packet/optical networks.
Ikeuchi, Tadashi   +5 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

A Scalable Benchmark as a Service Platform [PDF]

open access: yes, 2013
Load testing has always been a crucial and expensive activity for software companies. Classical solutions are a real burden to setup statically and their cost are prohibitive in terms of human and hardware resources. Cloud computing brings new opportunities to stress application scalability as load testing solutions can be provided on demand by the ...
Alain Tchana   +5 more
openaire   +1 more source

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