Results 71 to 80 of about 190,247 (255)
Structural Development for Well Service Activity in Limited Capacity Platform
The idea is to replace drilling rig, which is utilized for work over/well services activities, with working barge. The challenge comes from the operation and structural platform capacity since the majority of PHE WMO wellhead platform has limited ...
Esa Dewa Marciela +2 more
doaj +1 more source
Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan +7 more
wiley +1 more source
Aiming at the existing characters and deficiencies of the drilling experiment platform, a new kind of multifunctional drilling comprehensive experiment platform was designed.
TIAN JiaLin +7 more
doaj
Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son +3 more
wiley +1 more source
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier +12 more
wiley +1 more source
Objective The objective of this article is to identify perceptions of patients with systemic lupus erythematosus (SLE) regarding artificial intelligence (AI)–based online symptom assessment tools, and the potential of these tools to address diagnostic barriers.
Olivia A. Stein +7 more
wiley +1 more source
Objective Although the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semistructured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart +5 more
wiley +1 more source
Analysis of structure and dynamic characteristics for an electric tractor platform
The electrification of agricultural tractors introduces significant changes in vehicle architecture, mass distribution, and structural load paths. In particular, the transition from conventional diesel tractor platforms employing engine–axle integrated ...
Seung-Min Baek +5 more
doaj +1 more source
Objective Ambulatory care sensitive conditions (ACSCs) serve as indicators of access, quality, and performance of the health system. This study aimed to determine rheumatoid arthritis (RA)‐specific ACSCs for use in the evaluation of care system access and quality.
Kara Irwin +7 more
wiley +1 more source
Fully automated frame selection and region-of-interest placement in 2D shear wave elastography: reduced examination time with comparable reproducibility in diffuse liver disease [PDF]
Purpose This study evaluated the clinical utility of a fully automated two-dimensional shear wave elastography (2D-SWE) method incorporating automated frame selection and region-of-interest (ROI) placement algorithms in participants with diffuse liver ...
Hyo-Jin Kang +2 more
doaj +1 more source

