Results 71 to 80 of about 190,247 (255)

Structural Development for Well Service Activity in Limited Capacity Platform

open access: yesMATEC Web of Conferences, 2018
The idea is to replace drilling rig, which is utilized for work over/well services activities, with working barge. The challenge comes from the operation and structural platform capacity since the majority of PHE WMO wellhead platform has limited ...
Esa Dewa Marciela   +2 more
doaj   +1 more source

Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan   +7 more
wiley   +1 more source

NEW BALANCE METHOD OF DRILLING RIG LOAD OF MULTIFUNCTIONAL DRILLING COMPREHENSIVE EXPERIMENT PLATFORM

open access: yesJixie qiangdu, 2015
Aiming at the existing characters and deficiencies of the drilling experiment platform, a new kind of multifunctional drilling comprehensive experiment platform was designed.
TIAN JiaLin   +7 more
doaj  

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son   +3 more
wiley   +1 more source

Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

open access: yesArthritis Care &Research, EarlyView.
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier   +12 more
wiley   +1 more source

Artificial Intelligence–Based Online Symptom Assessment Tools for Systemic Lupus Erythematosus Diagnosis: Patient Perspectives

open access: yesArthritis Care &Research, EarlyView.
Objective The objective of this article is to identify perceptions of patients with systemic lupus erythematosus (SLE) regarding artificial intelligence (AI)–based online symptom assessment tools, and the potential of these tools to address diagnostic barriers.
Olivia A. Stein   +7 more
wiley   +1 more source

A Return to Normality: A Descriptive Qualitative Interview Study Exploring the Patient Experience of Gout Flare Resolution

open access: yesArthritis Care &Research, EarlyView.
Objective Although the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semistructured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart   +5 more
wiley   +1 more source

Analysis of structure and dynamic characteristics for an electric tractor platform

open access: yesScientific Reports
The electrification of agricultural tractors introduces significant changes in vehicle architecture, mass distribution, and structural load paths. In particular, the transition from conventional diesel tractor platforms employing engine–axle integrated ...
Seung-Min Baek   +5 more
doaj   +1 more source

The Development of Rheumatoid Arthritis‐Specific Ambulatory Care Sensitive Conditions: Results of a Consensus Process

open access: yesArthritis Care &Research, Accepted Article.
Objective Ambulatory care sensitive conditions (ACSCs) serve as indicators of access, quality, and performance of the health system. This study aimed to determine rheumatoid arthritis (RA)‐specific ACSCs for use in the evaluation of care system access and quality.
Kara Irwin   +7 more
wiley   +1 more source

Fully automated frame selection and region-of-interest placement in 2D shear wave elastography: reduced examination time with comparable reproducibility in diffuse liver disease [PDF]

open access: yesUltrasonography
Purpose This study evaluated the clinical utility of a fully automated two-dimensional shear wave elastography (2D-SWE) method incorporating automated frame selection and region-of-interest (ROI) placement algorithms in participants with diffuse liver ...
Hyo-Jin Kang   +2 more
doaj   +1 more source

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