Results 41 to 50 of about 450,650 (277)

From Network Effects to Data Network Effects: Enabling Ecosystemic Innovation for Sustainability

open access: yesM@n@gement
This paper distinguishes between traditional network effects and data network effects, showing how the latter become central levers of sustainability transitions by enhancing efficiency, equity, and resilience across ecosystems.
Wim Vanhaverbeke
doaj   +1 more source

The disease of corruption: views on how to fight corruption to advance 21st century global health goals [PDF]

open access: yes, 2016
Corruption has been described as a disease. When corruption infiltrates global health, it can be particularly devastating, threatening hard gained improvements in human and economic development, international security, and population health.
Clare, Jillian   +6 more
core   +1 more source

A Puff of Steem: Security Analysis of Decentralized Content Curation [PDF]

open access: yes, 2020
Decentralized content curation is the process through which uploaded posts are ranked and filtered based exclusively on users\u27 feedback. Platforms such as the blockchain-based Steemit employ this type of curation while providing monetary incentives to
  +3 more
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Towards Principles-Based Approaches to Governance of Health-Related Research Using Personal Data [PDF]

open access: yes, 2013
Technological advances in the quality, availability and linkage potential of health data for research make the need to develop robust and effective information governance mechanisms more pressing than ever before; they also lead us to question the ...
Alexy   +23 more
core   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Evolution of mobility governance in Flanders: opening up for bottom-up initiatives or suffering from lock-in? [PDF]

open access: yes, 2015
Mobility policy in Flanders lacks a clear discourse on implementing the policy objectives for 2020 and beyond. Though mobility planning can show success stories, mobility problems seem to aggravate.
Boelens, Luuk   +2 more
core   +1 more source

Poverty and social policy in Europe 2020: ungovernable and ungoverned [PDF]

open access: yes, 2014
This is a post-peer-review, pre-copy edited version of an article published in Policy and Politics. The definitive publisher-authenticated version of: Copeland, Paul, and Mary Daly. "Poverty and social policy in Europe 2020: ungovernable and ungoverned."
COPELAND, P, DALY, M
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Internet Utopianism and the Practical Inevitability of Law [PDF]

open access: yes, 2019
Writing at the dawn of the digital era, John Perry Barlow proclaimed cyberspace to be a new domain of pure freedom. Addressing the nations of the world, he cautioned that their laws, which were “based on matter,” simply did not speak to conduct in the ...
Cohen, Julie E.
core   +2 more sources

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