Results 61 to 70 of about 54,636 (301)

Research on Modeling and Framework of Building Information Model Cloud Platform Supporting Collaborative Governance [PDF]

Jisuanji gongcheng, 2016
In order to realize efficiently collaboration in the construction domain,this paper presents a Building Information Model(BIM) cloud platform modeling method for collaborative governance,proposes a BIM collaborative governance framework and divides ...
ZHANG Shaohua,JIAO Yi,CHEN Gang
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Research on technology framework of modern coal industry governance Platform based on the new generation information technologies

Meitan kexue jishu
In recent years, China's modern coal industry governance system cannot satisfy the high-quality development requirements of coal industry. To improve the capacity of government regulation, a complete set of coal industry governance platforms should be ...
Yahui HU, Yujiang ZHOU, Yihui PANG
doaj   +1 more source

Governing online platforms: Competition policy in times of platformization [PDF]

Telecommunications Policy, 2018
This paper argues that a paradigmatic change in competition policy is needed and empirically under way to cope with the challenges posed by economically strong online platforms and their big-data-based business models. Competition policy needs to move further away from its traditional price-oriented emphasis and increasingly focus on non-price ...
openaire   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Digital Exposure and Emotional Response: Public Discourse on Mandatory IP Location Disclosure in Chinese Social Media

Systems
This study examines the evolving use of social software to combat online disinformation by investigating Weibo users’ attitudes toward IP location disclosure as a measure of transparency and trustworthiness.
Yuehan Lu, Zerong Xie, Dickson K. W. Chiu, Eleanna Kafeza   +3 more
doaj   +1 more source

An Analytical study on Navigating Sustainability Challenges and Opportunities in the era of AI and the Gig Economy [PDF]

MATEC Web of Conferences
The gig economy, characterized by its flexible work arrangements and independent contractors, has witnessed rapid growth in recent years. However, it faces sustainability challenges related to worker welfare, income security, and job classification. This
Nimmagadda Babu, Vangaveti Yugandhar, Aaluri Suresh, Mallikarjuna Rao Ch., Singh Balpreet   +4 more
doaj   +1 more source

Governing invisibility in the platform economy: excavating the logics of platform care

Internet Policy Review, 2022
There has been a mounting research output on the social dimensions of the datafication, fragmentation and platformisation of infrastructures. This paper conceptually excavates the logics of ‘platform care’ as a continuation of historically invisibilised reproductive labour.
openaire   +4 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source