Results 41 to 50 of about 2,625 (216)

Data Governance Decisions for Platform Ecosystems [PDF]

Proceedings of the Annual Hawaii International Conference on System Sciences, 2019
Platform ecosystem has become an information system research subject after many years of industry success. The concept of platform ecosystem facilitates fast and self-growing of a platform by encouraging data contribution/consumption of multiple networks, and thus the importance and value of data in platforms is accentuated.
Sung Une Lee, Liming Zhu 0001, Ross Jeffery   +2 more
openaire   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Artificial Intelligence for Detecting Electoral Disinformation on Social Media: Models, Datasets, and Evaluation

Information
During elections, information manipulation on social media has accelerated the use of artificial intelligence, yet the evidence is difficult to interpret without an integrated view of methods, data, and evaluation.
Félix Díaz, Nhell Cerna, Rafael Liza, Bryan Motta   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Digital Identities and the Social Realm: How AI-Driven Platforms Reshape Participation, Recognition, and Group Dynamics

Societies
This paper argues that digital identity in AI-mediated environments has become a central mechanism through which contemporary societies organise recognition, participation, and belonging. Digital identity is no longer simply a technical representation of
Oluwaseyi B. Ayeni, Isabella Musinguzi-Karamukyo, Oluwakemi T. Onibalusi, Oluwajuwon M. Omigbodun   +3 more
doaj   +1 more source

Cloud Platform Support for API Governance [PDF]

2014 IEEE International Conference on Cloud Engineering, 2014
As scalable information technology evolves to a more cloud-like model, digital assets (code, data and software environments) increasingly require curation as web-accessible services. "Service-izing" digital assets consists of encapsulating assets in software that exposes them to web and mobile applications via well-defined yet flexible, network ...
Chandra Krintz, Hiranya Jayathilaka, Stratos Dimopoulos, Alexander Pucher, Rich Wolski, Tevfik Bultan   +5 more
openaire   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Personal Worship in Contemporary China: A Cultural and Theoretical Review in the Context of the C-Star Paradigm [PDF]

SHS Web of Conferences
This paper examines the phenomenon of personal worship in contemporary China through the lens of the C-Star paradigm. It argues that personal worship has shifted from a primarily state-orchestrated and institutionally anchored form of charisma to a ...
Zhang Yunfan
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source