Results 21 to 30 of about 1,229,988 (286)

USP15 regulates dynamic protein-protein interactions of the spliceosome through deubiquitination of PRP31. [PDF]

open access: yes, 2017
Post-translational modifications contribute to the spliceosome dynamics by facilitating the physical rearrangements of the spliceosome. Here, we report USP15, a deubiquitinating enzyme, as a regulator of protein-protein interactions for the spliceosome ...
Das, Tanuza   +6 more
core   +1 more source

Transcriptome dynamics in the asexual cycle of the chordate Botryllus schlosseri [PDF]

open access: yes, 2016
Background: We performed an analysis of the transcriptome during the blastogenesis of the chordate Botryllus schlosseri, focusing in particular on genes involved in cell death by apoptosis. The tunicate B.
Ballarin, Loriano   +7 more
core   +3 more sources

Repress/redress: What the “war on terror” can teach us about fighting misinformation

open access: yesHarvard Kennedy School Misinformation Review, 2020
Misinformation, like terrorism, thrives where trust in conventional authorities has eroded. An informed policy response must therefore complement efforts to repress misinformation with efforts to redress loss of trust.
Alexei Abrahams, Gabrielle Lim
doaj   +1 more source

Digital Platform Regulation

open access: yes, 2022
This Open Access volume provides an in-depth exploration of global policy and governance issues related to digital platform regulation. With an international ensemble of contributors, the volume has at its heard the question: what would actually be involved in digital platform regulation?’. Once a specialised and niche field within internet and digital
Flew, Terry, Martin, Fiona R.
openaire   +3 more sources

The Twitter origins and evolution of the COVID-19 “plandemic” conspiracy theory

open access: yesHarvard Kennedy School Misinformation Review, 2020
Tweets about “plandemic” (e.g., #plandemic)—the notion that the COVID-19 pandemic was planned or fraudulent—helped to spread several distinct conspiracy theories related to COVID-19.
Matthew D. Kearney   +2 more
doaj   +1 more source

Constitutive Regulation as a Compromise for Disruptive Innovation?

open access: yesTechnology and Regulation
This article explores how constitutive regulation can function as a response to disruptive innovation, using the French platform regulator ARPE as a case study.
Archer Buissink
doaj   +1 more source

Answering impossible questions: Content governance in an age of disinformation

open access: yesHarvard Kennedy School Misinformation Review, 2020
The governance of online platforms has unfolded across three eras – the era of Rights (which stretched from the early 1990s to about 2010), the era of Public Health (from 2010 through the present), and the era of Process (of which we are now seeing the ...
John Bowers, Jonathan Zittrain
doaj   +1 more source

Modeling and control of complex dynamic systems: Applied mathematical aspects [PDF]

open access: yes, 2012
The concept of complex dynamic systems arises in many varieties, including the areas of energy generation, storage and distribution, ecosystems, gene regulation and health delivery, safety and security systems, telecommunications, transportation networks,
Gao, Chuanhou, Gao, Zhiwei, Kong, Dexing
core   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Misleading tobacco content is on the rise on YouTube

open access: yesHarvard Kennedy School Misinformation Review, 2020
A content analysis of popular videos on YouTube containing tobacco-relevant material revealed five categories of misleading content about tobacco use in 2013. A re-examination in 2019 of the most heavily viewed exemplars of these categories identified in
Daniel Romer   +2 more
doaj   +1 more source

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