Results 41 to 50 of about 490,118 (263)

Platform adaptation to regulation: The case of domestic cleaning in Europe

open access: yesJournal of Industrial Relations, 2023
While online platforms were initially applauded for improving services in a range of sectors, they are currently being criticized for ignoring laws and regulations. We analyse the evolution of Helpling – the largest domestic cleaning platform company in Europe – by focusing on the ways that Helpling has adapted its platform to regulations in five ...
Nikolaos Koutsimpogiorgos   +2 more
openaire   +5 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Unveiling ‘Algorithm Governance’

open access: yesWeizenbaum Journal of the Digital Society
Research on platform work has primarily focused on analyzing how algorithmic management influences working conditions by empowering platforms to govern digitally-delivered services.
Valeria Pulignano
doaj   +1 more source

Distinct Microbial Communities Trigger Colitis Development upon Intestinal Barrier Damage via Innate or Adaptive Immune Cells

open access: yesCell Reports, 2017
Summary: Inflammatory bowel disease comprises a group of heterogeneous diseases characterized by chronic and relapsing mucosal inflammation. Alterations in microbiota composition have been proposed to contribute to disease development, but no uniform ...
Urmi Roy   +9 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Cooperation or Confrontation? An Evolutionary Game Study on Content Clipping Authorization in Live Streaming E-Commerce Under Platform Regulation

open access: yesGames
The rapid rise of live-streaming e-commerce has fostered a new “content clipping” model, in which secondary creators edit and republish anchors’ live-streaming content to promote product sales. While this model can expand market reach and enhance revenue,
Feng Luo, Xinmiao Zhao, Tiantong Xu
doaj   +1 more source

Reframing platform power

open access: yesInternet Policy Review, 2019
This article addresses the problem of platform power by probing current regulatory frameworks’ basic assumptions about how tech firms operate in digital ecosystems.
José van Dijck   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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