Results 51 to 60 of about 1,248,661 (307)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Unveiling ‘Algorithm Governance’

Weizenbaum Journal of the Digital Society
Research on platform work has primarily focused on analyzing how algorithmic management influences working conditions by empowering platforms to govern digitally-delivered services.
Valeria Pulignano
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Regulating TNCs: Should Uber and Lyft Set Their Own Rules? [PDF]

, 2019
We evaluate the impact of three proposed regulations of transportation network companies (TNCs) like Uber, Lyft and Didi: (1) a minimum wage for drivers, (2) a cap on the number of drivers or vehicles, and (3) a per-trip congestion tax.
Li, Sen, Poolla, Kameshwar, Tavafoghi, Hamidreza, Varaiya, Pravin   +3 more
core   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Cooperation or Confrontation? An Evolutionary Game Study on Content Clipping Authorization in Live Streaming E-Commerce Under Platform Regulation

Games
The rapid rise of live-streaming e-commerce has fostered a new “content clipping” model, in which secondary creators edit and republish anchors’ live-streaming content to promote product sales. While this model can expand market reach and enhance revenue,
Feng Luo, Xinmiao Zhao, Tiantong Xu
doaj   +1 more source

Distinct Microbial Communities Trigger Colitis Development upon Intestinal Barrier Damage via Innate or Adaptive Immune Cells

Cell Reports, 2017
Summary: Inflammatory bowel disease comprises a group of heterogeneous diseases characterized by chronic and relapsing mucosal inflammation. Alterations in microbiota composition have been proposed to contribute to disease development, but no uniform ...
Urmi Roy, Eric J.C. Gálvez, Aida Iljazovic, Till Robin Lesker, Adrian J. Błażejewski, Marina C. Pils, Ulrike Heise, Samuel Huber, Richard A. Flavell, Till Strowig   +9 more
doaj   +1 more source

Characterization of cephalic and non-cephalic sensory cell types provides insight into joint photo- and mechanoreceptor evolution

eLife, 2021
Rhabdomeric opsins (r-opsins) are light sensors in cephalic eye photoreceptors, but also function in additional sensory organs. This has prompted questions on the evolutionary relationship of these cell types, and if ancient r-opsins were non ...
Roger Revilla-i-Domingo, Vinoth Babu Veedin Rajan, Monika Waldherr, Günther Prohaczka, Hugo Musset, Lukas Orel, Elliot Gerrard, Moritz Smolka, Alexander Stockinger, Matthias Farlik, Robert J Lucas, Florian Raible, Kristin Tessmar-Raible   +12 more
doaj   +1 more source

Modelling of Stray Currents Near a Railway Platform [PDF]

, 2017
The article describes simulations of the occurrence of stray currents in the vicinity of a SUDOPtype railway platform. Stray currents occur in the vicinity of a railway platform during the passage of a railway vehicle.
Cigánek, Jiří, Mohylová, Jitka, Zajaczek, Stanislav, Ďurica, Maroš   +3 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source