Results 61 to 70 of about 5,639,155 (335)
Profound effect of profiling platform and normalization strategy on detection of differentially expressed microRNAs [PDF]
, 2012 Adequate normalization minimizes the effects of systematic technical variations and is a prerequisite for getting meaningful biological changes. However, there is inconsistency about miRNA normalization performances and recommendations.
Wagner, Carola +4 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
GamesThe rapid rise of live-streaming e-commerce has fostered a new “content clipping” model, in which secondary creators edit and republish anchors’ live-streaming content to promote product sales. While this model can expand market reach and enhance revenue,
Feng Luo, Xinmiao Zhao, Tiantong Xu
doaj +1 more source
The changing shape of platform regulation
, 2020 Whether and how to regulate companies that provide social media or search services are key questions that governments around the world are grappling with, as both users and regulators worry about the extent of these tech giants’ influence.
Kretschmer, Martin, Schlesinger, Philip
core
Making Sense of EU Platform Regulation
, 2022 The platforms that hold the power in the digital economy, and the politics that surround them, are a central topic in contemporary political economy. The EU is widely perceived as a digital laggard, as it is home to very few leading digital corporations,
Staab, Philipp +2 more
core +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Cell Reports, 2017 Summary: Inflammatory bowel disease comprises a group of heterogeneous diseases characterized by chronic and relapsing mucosal inflammation. Alterations in microbiota composition have been proposed to contribute to disease development, but no uniform ...
Urmi Roy +9 more
doaj +1 more source
The Emergence of Platform Regulation in the UK
Weizenbaum Journal of the Digital Society, 2022 Online platforms have emerged as a new kind of regulatory object. In this article, we empirically map the emergence of the field of platform regulation in one country: the United Kingdom (UK).
Martin Kretschmer +2 more
doaj +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source