Results 61 to 70 of about 13,415,375 (294)
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
, 2020 This Special Issue “Innovative and Applied Research on Platinum-group and Rare Earth Elements” is dedicated to the work and memory of Demetrios Eliopoulos, IGME (Institute of Geology and Mineral Exploration), Greece who passed away on 19 ...
Giorgio Garuti +5 more
core +1 more source
Redox control of the partitioning of platinum and palladium into magmatic sulfide liquids
Communications Earth & EnvironmentThe partitioning behavior of platinum group elements in magmas is critical for their use as tracers of planetary accretion and in understanding magmatic sulfide deposits.
Wanying Wang, Yuan Li
doaj +1 more source
Aging and Cancer, EarlyView.Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi +3 more
wiley +1 more source
Processes leading to concentration of platinum-group elements in chromite rich rocks [PDF]
, 2014 Platinum-group elements are enriched in the ultramafic parts of the Stillwater, Bushveld and Great Dyke Complexes.
Prichard, Hazel Margaret +5 more
core
Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni +19 more
wiley +1 more source
Platinum-group minerals in the Jinchuan complex, China
, 2005 Platinum-group elements (PGE) and minerals (PGM), most commonly froodite (PdBi2), michenerite (PdTeBi), padrnaite (PdBiSe), sperrylite (PtAsz) and irarsite (IrAsS), have been analysed from the Jinchuan Ni-Cu-PGE sulphide deposit in the south western ...
Zhou, MF +4 more
core
Clinical resistance to platinum chemotherapy in ovarian cancer [PDF]
, 2009 Platinum drugs are the most active agents in ovarian cancer. Their cytotoxicty results from DNA crosslinking. High tumour response rates are seen, but 80 % of patients relapse. Major mechanisms of platinum resistance in patients remain to be established.
Newton, C., Newton, C
core
Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino +25 more
wiley +1 more source