Results 41 to 50 of about 407,344 (301)

Unusual DNA binding modes for metal anticancer complexes [PDF]

, 2009
DNA is believed to be the primary target for many metal-based drugs. For example, platinum-based anticancer drugs can form specific lesions on DNA that induce apoptosis.
Pizarro, Ana M., Sadler, P. J.
core   +1 more source

Insight into fuel injection aging effect on deactivation of PtPd bimetallic supported diesel oxidation catalyst: From engine performance evaluation of monolithic catalysts to microscopic characterization of active species

Fuel Processing Technology
In this study, a comparative experimental study was carried out on DOC catalysts with different aging times (0 h, 40 h, 80 h) by using engine. Emission data were collected through engine testing, and the catalytic behavior of DOC catalysts was analyzed ...
Dezhi Ren, Xin Dai, Jingfang Zhu, Fei Yu, Shunhong Li, Chaoqiang Wang, Jie Yan, Shiying Chang, Dongxia Yang, Yunkun Zhao   +9 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Effect of Cu species on N2O formation in the NH3-SCR reaction over Cu-SSZ-13 [PDF]

RSC Advances
This work systematically investigates the effect of Cu/Al ratio on NOx conversion, N2O formation, NH3 oxidation, and hydrothermal stability over Cu-SSZ-13 catalysts under simulated diesel-exhaust NH3-SCR conditions.
Feng Feng, Xiankun Wang, Jiangli Ma, Hongyao Luo, Han Zhao, Dongxia Yang, Kongzhai Li, Hua Wang   +7 more
doaj   +1 more source

Nano Si‐Doped Ruthenium Oxide Particles from Caged Precursors for High‐Performance Acidic Oxygen Evolution

Advanced Science, 2023
RuO2 is well known as the benchmark acidic oxygen evolution reaction (OER) catalyst, but its practical application has been impeded by its limited durability.
Chunxiang Liu, Yunbo Jiang, Teng Wang, Qiaosheng Li, Yuzhou Liu   +4 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Cu-Ni Captures Platinum Group Metals from Spent Automotive Exhaust Catalysts

Separations
Platinum group metals (PGMs) are strategic metals, and recycling PGMs in spent automobile exhaust catalysts (SACs) is a key path to alleviate the contradiction between resource supply and demand.
Jiahao Li, Jibiao Han, Han Yang, Guozhen Wang, Kuo Liu, Lang Liu, Yong Li, Qingfeng Xiong, Junmei Guo, Bin Yang, Haigang Dong   +10 more
doaj   +1 more source

Material and heat flow analysis in thermal energy storage and transport system utilizing unused heat from bagasse boiler

Mechanical Engineering Journal, 2016
Sugar production is the main industry in Tanegashima, Japan. Whilst the sugar mill recycles sugarcane bagasse as a fuel, it concurrently generates large amounts of unused 200 °C heat during operation.
Shoma FUJII, Yuichiro KANEMATSU, Yasunori KIKUCHI, Takao NAKAGAKI   +3 more
doaj   +1 more source

Highly Active Pt-Co/C Nanoparticles: Controllable Preparation and Catalytic Performance for Methanol Electro-oxidation

International Journal of Electrochemical Science, 2020
Carbon-supported platinum (Pt) for oxygen reduction reaction plays an important role in the operation of direct methanol fuel cells (DMFCs). However, complete oxidation of ethanol is difficult due to the low chemical activity of Pt / C.
Yiqi Cui, Shuaikang Ying, Hongzhong Cai, Yan Wei, Changyi Hu   +4 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source