Results 41 to 50 of about 419,192 (303)

Use of top-down and bottom-up fourier transform ion cyclotron resonance mass spectrometry for mapping calmodulin sites modified by platinum anticancer drugs [PDF]

, 2011
Calmodulin (CaM) is a highly conserved, ubiquitous, calcium-binding protein; it binds to and regulates many different protein targets, thereby functioning as a calcium sensor and signal transducer.
Lin, Tzu-Yung, Sadler, P. J., Steve L. Van Orden, Yulin Qi, Qi, Yulin, Yao Zhao, Peter B. O’Connor, Peter J. Sadler, Pizarro, Ana M., Ana M. Pizarro, Barrow, Mark P., O’Connor, Peter B., Huilin Li, Tzu-Yung Lin, Van Orden, Steve L., Zhao, Yao, (Researcher in chemistry), Mark P. Barrow, Li, Huilin   +17 more
core   +1 more source

Increased long-term stress-rupture life of a nickel-based superalloy with relatively homogeneous duplex grain size distributions

Materials & Design
Effect of duplex grain size distributions on long-term stress-rupture life of Nimonic 80A had been investigated. Non-homogeneous duplex grain size distributions greatly reduce stress-rupture life.
Yulai Xu, Zhilong Tan, Xingyu Wang, Xianhui Luo, Xiaofei Wu   +4 more
doaj   +1 more source

An integrated cross-scale computational approach for understanding and optimizing continuous-flow extraction of precious metals

Chemical Engineering Journal Advances
The extraction of platinum group metals (PGMs) from secondary resources is essential for sustainable resource cycles, yet process design often relies on empirical methods due to a lack of multiscale understanding.
Xiangguang Bi, Jifan Li, Jianrui Bai, Pengfei Fu, Zejin Yu, Hui Liu, Aoxue Sun, Jun Lu, Junmei Guo, Shan Qing, Xiao Duan   +10 more
doaj   +1 more source

Aging hardening characteristic and electrical conductivity of Cu-Cr-Zr-Mo in situ composite

Science and Engineering of Composite Materials, 2016
Cu-0.85Cr-0.5Zr-0.5Mo in situ composite was prepared by continuous casting, cold drawing, and aging treatment. By means of the analysis of microhardness, electrical conductivity, and transmission electron microscopy, the aging characteristics and ...
Wang Song, Zheng Tingting, Xie Ming, Chen Yongtai, Zhang Jiming   +4 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Insight into fuel injection aging effect on deactivation of PtPd bimetallic supported diesel oxidation catalyst: From engine performance evaluation of monolithic catalysts to microscopic characterization of active species

Fuel Processing Technology
In this study, a comparative experimental study was carried out on DOC catalysts with different aging times (0 h, 40 h, 80 h) by using engine. Emission data were collected through engine testing, and the catalytic behavior of DOC catalysts was analyzed ...
Dezhi Ren, Xin Dai, Jingfang Zhu, Fei Yu, Shunhong Li, Chaoqiang Wang, Jie Yan, Shiying Chang, Dongxia Yang, Yunkun Zhao   +9 more
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Effect of Cu species on N2O formation in the NH3-SCR reaction over Cu-SSZ-13 [PDF]

RSC Advances
This work systematically investigates the effect of Cu/Al ratio on NOx conversion, N2O formation, NH3 oxidation, and hydrothermal stability over Cu-SSZ-13 catalysts under simulated diesel-exhaust NH3-SCR conditions.
Feng Feng, Xiankun Wang, Jiangli Ma, Hongyao Luo, Han Zhao, Dongxia Yang, Kongzhai Li, Hua Wang   +7 more
doaj   +1 more source

Photoactivation of trans diamine platinum complexes in aqueous solution and effect on reactivity towards nucleotides [PDF]

, 2010
We show that UVA irradiation (365 nm) of the Pt-IV complex trans,trans,trans-[(PtCl2)-Cl-IV(OH)(2)(dimethylamine) (isopropylamine)] (1), induces reduction to Pt-II photoproducts.
Pizarro, Ana M., Sadler, P. J., Cubo, Leticia, Navarro-Ranninger, Carmen, Salassa, Luca, Quiroga, Adoracion G.   +5 more
core   +1 more source