Results 171 to 180 of about 228,477 (296)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

The Circumvention of UEFA\u27s Financial Fair Play Rules Through the Influx of Foreign Investments

, 2018
European football is undergoing rapid changes spurred on by enormous investments from around the globe. Although regulations exist to curtail teams buying their way to success, foreign investors have become ingenious at circumventing Financial Fair Play ...
Sims, Patrick J.
core  

Social connectedness in mobile gaming: how family dynamics shape children's virtual interactions. [PDF]

Front Psychiatry
Pang L, Mustafa SE, Gong J, Cheng Y.
europepmc   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Adventures in the Play-Ritual Continuum

The junctions between play and ritual are many and complex. Play is for fun and joy, but it also demands a total commitment and serious respect for rules. Rituals involve nearly endless varieties of social arrangements and can truly transform people, but
Pisera, Sallie Anna, Young, Sheila M., Lindelöf, Karin S., Gradén, Lizette, Eggel, Ruth Dorothea, Löfgren, Jakob, Tolgensbakk, Ida, Jansson, Hanna, Poole, Simon, Kjus, Audun, Herd, Katarzyna, O’Carroll, Clíona, Woube, Annie   +12 more
core  

When Policy Meets Practice: Medical Residents and the Governance of Smartphone Use for Communication in Clinical Settings. [PDF]

Healthcare (Basel)
Barr NG, Randall GE.
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Policy proposals by children during the COVID-19 pandemic through the global child rights dialogues in Japan, Sweden and Tanzania. [PDF]

BMJ Paediatr Open
Takeuchi H, Tungu M, Baroudi M.
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

More Than Their Bodies. Aesthetic Dimensions of Nursing Care to People With Eating Disorders. [PDF]

Scand J Caring Sci
Herholdt-Lomholdt SM, Brinchmann BS.
europepmc   +1 more source