Results 31 to 40 of about 228,477 (296)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Playing with the Rules [Elektronisk resurs] : Social and Cultural Aspects of Game Rules in a Console Game Club

open access: yes, 2007
In this study of a Swedish console game club I have looked at how the rules of the games are connected to the social and cultural aspects of the context that the games are played in. I have devoted special attention to the game Super Smash Bros.
Jakobsson, Mikael, Jakobsson, Mikael,
core   +1 more source

Match play performance characteristics that predict post-match creatine kinase responses in professional rugby union players [PDF]

open access: yes, 2014
Background: Rugby union players can take several days to fully recover from competition. Muscle damage induced during the match has a major role in player recovery; however the specific characteristics of match play that predict post-match muscle damage ...
Harrington, Bradley J   +25 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Playing with Rules : Exploring Practical and Theoretical Potentials of Rules as a Play-Centric Tool [PDF]

open access: yes, 2022
This thesis presents an exploration of how rule reflection can practically be applied to consciously form play-practices. It aims to bring a discussion regarding rules, a historically formalist conceptual tool, to expand its use to play-centric domains ...
Balcı, Doruk
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

OR Analysis of Sporting Rules – a survey [PDF]

open access: yes, 2012
This paper surveys the academic OR/analytics literature describing research into the laws and rules of sports and sporting competitions. The literature is divided into post hoc analyses and proposals for future changes, and is also divided into laws ...
Wright, Mike
core  

Playing by the rules. [PDF]

open access: yesACM Queue, 2006
Some of my favorite childhood memories are of playing games with my sister—both structured games such as Monopoly or hopscotch and imagination-fueled games such as cops and robbers or roller derby girls. Regardless of whether the game had established regulations, often our play would devolve into what I call Calvinball, a term coined in the comic strip
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Langage et construction de règles en jeux collectifs

open access: yesRecherches en Éducation, 2016
In a socio-constructivist didactic physical education teaching model, 6 years old pupils have to play at a collective ball game. At the same time, they have to tell each other action rules to be better players.
Florence Darnis, Lucile Lafont
doaj   +1 more source

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