Results 31 to 40 of about 202,356 (249)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Jurnal Manajemen Teori dan Terapan, 2016 This study would examined empirically which one of these ethical criteria, namely self-interest, company, interest, efficiency, friendship, team play, social responsibility, personal morality, rules and procedures, and the law or professional code ...
Siti Sulasmi, IGM Dwi Widhianto
doaj +1 more source
Biology of Sport, 2023 This study assessed the effects of playing freely and introducing artificial rules on individual tactical behaviour during the team-possession game phase in two youth soccercategories.
Asier Gonzalez-Artetxe +4 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Jeux de rôles pour enfants : une nouvelle forme de fiction ludique
Strenae, 2011 How can we ethnographically map the place of fictional invention in children? Here we present a case study of a practice at the crossroads of spontaneous children's role-play and life-size adult role-play. Conducted in the form of a summer workshop, this
Sébastien Kapp
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
ACM Queue, 2006 Some of my favorite childhood memories are of playing games with my sister—both structured games such as Monopoly or hopscotch and imagination-fueled games such as cops and robbers or roller derby girls. Regardless of whether the game had established regulations, often our play would devolve into what I call Calvinball, a term coined in the comic strip
openaire +2 more sources
Childhood and fantasy game in the digital world
Revista Sobre la Infancia y la Adolescencia, 2015 We begin with questions that offer multiple answers and open a debate which will give a more complete answer with richer content when possible. Who sets the rules to play in the Children’s digital world?
Lluís Andreu Bertran
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Axiological and Methodological Analysis of Folk Games
Психолого-педагогические исследования, 2021 Play is defined as a special form of free activity according to the rules, that, unlike work, does not produce an alienable product. The socio-psychological mechanism of the influence of the conditions of the game on the participants is considered ...
Teplova A.B., Chernushevich V.A.
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source