Results 51 to 60 of about 195,998 (250)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Las manifestaciones del juego limpio en el ejercicio de la actividad cinegética

open access: yesRevista Vasca de Administración Pública, 2011
From yesteryear, there are a collection of rules which make up the action of hunting with the scope of protecting a scenario where the hunters¿ advantage is not to be superior as making the animal impossible or very difficult to get away from the tights ...
José María Pérez Monguió
doaj   +1 more source

Playing by the Rules [PDF]

open access: yesQueue, 2006
Some of my favorite childhood memories are of playing games with my sister—both structured games such as Monopoly or hopscotch and imagination-fueled games such as cops and robbers or roller derby girls. Regardless of whether the game had established regulations, often our play would devolve into what I call Calvinball, a term coined in the comic strip
openaire   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Having Linguistic Rules and Knowing Linguistic Facts

open access: yesThe Baltic International Yearbook of Cognition, Logic and Communication, 2010
<p>'Knowledge' doesn't correctly describe our relation to linguistic rules. It is too thick a notion (for example, we don't believe linguistic rules).
Peter Ludlow
doaj   +1 more source

Hoarding Concept according to Hinduism, Judaism and Islam

open access: yesJournal of Islamic and Religious Studies, 2016
Hoarding is considered (Ihtikar) very abhorring and objectionable. It is the practice of keeping something in store and not bringing the same to the market so that prices may rise owing to this artificial dearth of supply in the market. Each religion of
Muhammad Anees Khan, Irfan ullah
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Strategic rule breaking: Time wasting to win soccer games.

open access: yesPLoS ONE, 2019
Rules regulate behavior, but in competitive contexts they also create incentives for rule-breaking because enforcement is imperfect. Sports is a prime example of this, and one that lends itself well to investigation because strategic rule-breaking is ...
Henrich R Greve   +2 more
doaj   +1 more source

Literaire polemiek als gevecht tussen spel en ernst: Een exercitie in literaire speltheorie

open access: yesLiterator, 1991
This article is a serious exercise in literary game theory, exploring literary polemics from a playful perspective based on the work of Huizinga and Caillois.
J. Flamend
doaj   +1 more source

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