Results 71 to 80 of about 195,998 (250)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Physical Culture and Sport: Studies and Research, 2014 The article has strictly a theoretical and non-empirical character. The author presents examples resulting from various observations. The aim of the paper is to present the causes, functions, and results of fouls, fouling, and foul play.
Kosiewicz Jerzy
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
SecEd, 2008 Are you ready for the new immigration system for international students, which is set to launch in March 2009? SecEd legal expert Helen Rideout explains how it affects you
openaire +3 more sources
Not Playing by the Rules: Exploratory Play, Rational Action, and Efficient Search
Open Mind, 2023 Junyi Chu, Laura E. Schulz
doaj +1 more source
Book Review: Ranking: The Unwritten Rules of the Social Game We All Play
Frontiers in Psychology, 2021 Basabdatta Sen Bhattacharya
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Application of classification rules to Italian ports
Promet (Zagreb), 2014 In this paper, the existing rules commonly used for port traffic comparison are described. These rules provide weighting factors for each freight category in order to make them comparable and exploitable for port ranking.
Marino Lupi +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source