Results 131 to 140 of about 8,044,780 (313)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Broadening the Mission: Research Activity among University Labor Education/Labor Studies Professionals [PDF]

, 1990
[Excerpt] This study examines research activity among university and college labor education/labor studies professionals. Using data gathered in a survey of faculty employed in the field, the paper presents information concerning the extent and focus of ...
Clark, Paul F., Gray, Lois S.
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Moderating role of place identity in parental support of children’s folk games in Chinese neighbourhoods

Cogent Social Sciences
Children’s physical and mental health are currently facing serious challenges due to decreasing outdoor activity time and an increasingly homogeneous selection of accessible games.
Xin Zhao, Norhuzailin Hussain, Shureen Faris Abdul Shukor   +2 more
doaj   +1 more source

Inorganic materials in industrial processes [PDF]

, 2015
Although inorganic materials represent a small number to the extreme number of the organic ones, they play a number of crucial roles in several processes of industrial interest.
Demadis, Konstantinos D.
core  

Playing in the Sandbox: A Study on the Usability of Seccomp

CoRR
Sandboxing restricts what applications do, and prevents exploited processes being abused; yet relatively few applications get sandboxed: why? We report a usability trial with 7 experienced Seccomp developers exploring how they approached sandboxing an application and the difficulties they faced. The developers each approached sandboxing the application
Maysara Alhindi, Joseph Hallett
openaire   +3 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

ÖZLEM ÜNALAN, YEDİDEN YETMİŞE BAYBURT'TA OYUN/ Kültürel Değişim Ekseninde Çocuk, Genç, Yetişkin Oyunları ve Halk Tiyatrosu, Bursa: Emin Yayınları, 2024, ISBN: 978- 625-6563-67-1

Culture and Civilization
Oyun, yaş gözetmeksizin her bireyin hayatında önemli bir yer tutar. Yetişkinler içingenellikle eğlenme, dinlenme ve boş zamanı keyifli bir şekilde değerlendirme aracı olanoyun; çocuklar için sosyal, bilişsel ve duyuşsal gelişimi destekleyen aynı zamanda ...
Şeyma Arıkan Güllü
doaj   +1 more source