Results 121 to 130 of about 2,097,332 (298)

Effects of psychological interventions based on play therapy on clinical symptoms of restlessness in preschool children

مجله علوم روانشناختی, 2015
Currently family based Therapies have been considered one of the important approaches to prevent children from psychological pathologies these approaches have been acknowledged by parents and professionals as well.
Saee'd Rahimi, Bagher Ghobari Bonab, GholamAli Afrooz, Salar Faramarzi   +3 more
doaj  

Virtual Family Play Therapy: A Clinician's Guide to using Directed Family Play Therapy in Telemental Health. [PDF]

Contemp Fam Ther, 2023
Smith T, Norton AM, Marroquin L.
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Play Therapy As Effective Options for School-Age Children With Emotional and Behavioral Problems: A Case Series. [PDF]

Cureus, 2023
Gupta N, Chaudhary R, Gupta M, Ikehara LH, Zubiar F, Madabushi JS.   +5 more
europepmc   +1 more source

Measurement of the effect of digital play therapy using biological information [PDF]

, 2017
Giannopulu, Irini, Horie, Ryota, Hoshina, Atsushi, Sugaya, Midori   +3 more
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Play therapy: A window into the child's world

Archives of Mental Health, 2011
Play therapy is a developmentally responsive modality uniquely suited for children to help prevent or resolve psychosocial difficulties and achieve optimal growth and development.
K J Vijay Sagar
doaj  

The Effectiveness of Play Therapy on Symptoms of Emotional, Behavioral and Problem-Solving Skills in Foster Care Children [PDF]

Taṣvīr-i salāmat, 2018
Background and Objectives : Play is defined as any type of targeted physical or mental activity which is done individually or in group and develops children needs. This study aimed at effectiveness of play therapy on symptoms of emotional, behavioral and
Sakineh Jalali Dizaji, Parviz Karimi Sani   +1 more
doaj  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source