Results 81 to 90 of about 2,097,332 (298)

The Curative Power of Play: The Voices of Therapists around the World [PDF]

open access: yes, 2016
It is important for all therapists to be culturally sensitive to children and their eco-systems as well as to be aware of the current trends and the changing application of play as a healing agent.
Bowers, Anna Lee   +2 more
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

The Effect of Play Therapy Based on Cognitive-behavioral Approach on Academic Achievement and Self-esteem of Students with Special Learning Disabilities

open access: yesپژوهان, 2020
Background and Objectives: The aim of this study was to determine the role of play therapy based on cognitive-behavioral approach in increasing self-esteem and improving academic performance of students with special learning disabilities (inadequacy and ...
Farzaneh Abbaslo
doaj  

Psychotherapeutic Techniques and Play Therapy with Children Who Experienced Trauma: A Review of The Literature [PDF]

open access: yes, 2011
This research examined the use of Play Therapy with children who have experienced emotional, physical or psychological trauma. Past research supports other therapeutic modalities as being effective with children after a traumatic experience, though the ...
LaMotte, Julia
core   +1 more source

Autophagy in DNA Damage Response [PDF]

open access: yes, 2015
DNA damage response (DDR) involves DNA repair, cell cycle regulation and apoptosis, but autophagy is also suggested to play a role in DDR. Autophagy can be activated in response to DNA-damaging agents, but the exact mechanism underlying this activation ...
Elzbieta Pawlowska   +4 more
core   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Play Therapy Untuk anak-anak Korban Bencana Alam Yang Mengalami Trauma (Post Traumatic Stress Disorder/PTSD)

open access: yesPsympathic: Jurnal Ilmiah Psikologi, 2016
Anywhere in the world, natural disasters events cause loss of life, moreover a deep sorrow and fear for the victims. They were in a state of very uneasy, very scared, never-ending anxiety, and become prone to panic. These conditions called post-traumatic
Endah Nawangsih
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Comparison of the Effectiveness of Cognitive Play Therapy and Computer-based Working Memory Training on Impulsivity of Children with Attention Deficit Hyperactivity Disorder in Farsan City [PDF]

open access: yesپژوهان
Background and Objectives: The present study was conducted with the aim of comparing the effectiveness of cognitive play therapy and computer-based working memory training on the impulsivity of children with Attention Deficit Hyperactivity Disorder (ADHD)
Kamran Heidari Farsani   +2 more
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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