Results 61 to 70 of about 3,897,063 (291)

The Play of Play

open access: yesSpeki. Nordic Philosophy and Education Review
This article takes three steps to explore 'play' as an educational concept. In the first step, we analyse 'play' as a "playful attitude" with reference to the theories of Jacques Henriot and Erving Goffman. Here, we suggest that play can entail not simply the activity of playing, but also the player’s attitude and the surrounding social frame.
Kjetil Horn Hogstad, Caroline Cruaud
openaire   +1 more source

Goethe’s Early Historical Dramas

open access: yesHumanities
In this essay, Goethe’s early historical plays, Götz von Berlichingen, published in 1773, and Egmont, published only in 1787, are compared. So far, scholarly work has not recognized enough of the differences between both works.
Marc Jeremias Schweissinger
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

The best men's monologues from new plays, 2020

open access: yes, 2021
Renowned editor Lawrence Harbison brings together approximately one-hundred never-before-published men's monologues for actors to use for auditions and in class, all from recently produced plays.
Harbison, Lawrence ca. 20. Jh.
core  

PARTICULARITIES OF COMMUNICATION IN RURAL TOURISM [PDF]

open access: yesScientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2014
The social aspect of rural tourism enhances its value as a communicative process because Tourism is an industry with a difference. There is an undeniable exchange between places and people. This exchange is what is meant bycommunication.
Svetlana SASU, Svetlana DARII
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Intimidades de un pensamiento desacatado

open access: yesFilología, 2014
En este breve ensayo se plantea la configuración de una tópica intimista y primaria, una esfera afectiva en la que Macedonio se refugió a lo largo de toda su vida y en cuyo hábitat emprendió su trabajo intelectual vitalicio del pensar-escribiendo.
Ana Camblong
doaj  

Przedstawienia purimowe

open access: yesPamiętnik Teatralny, 1992
The first Polish language presentation of the oldest Yiddish theatrical tradition, along with its religious and social contexts. The author gives a description of the Purim festivities and mentions the traditional dislike expressed by religious circles ...
Tomasz Kuberczyk
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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