Results 71 to 80 of about 3,897,063 (291)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Male Bonding in Shakespeare's Plays
Ikala: Revista de Lenguaje y Cultura, 1998 Shakespeare throughout his plays, tradegies and comedies, makes an ample representation of male bonding at different levels, and although he shows predilection for this kind of relationship he never idealizes it.
Beatriz Aguirre
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An Analysis Of The Lived Experience Of Visually Impaired Students From Childhood Plays [PDF]
Taḥqīqāt-i ̒Ulūm-i RaftārīAim and Background: Play is one of the ways children learn about the social world, and impaired vision affects how they play and use toys. This study aimed to explore the lived experience of visually impaired students from childhood plays.
Sara Nejatifar +2 more
doaj
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Studies in Digital HeritageThis paper proposes a serious game that explores and digitally reconstructs the soundscape of the relocated Ottoman Sabīl (water dispensary) wa-Kuttāb (Quran elementary school) of Ismāʿīl al-Maghlawī, in historic Cairo, dated to 1657 CE.
Aliaa El-Dardiry +2 more
doaj +5 more sources
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
American Journal of Islam and Society, 2004 Like most of the other anthologies edited by Salma Khadra Jayyusi, Short Arabic Plays is a collection of translated Arabic literary works focused around one particular genre. This anthology, part of Jayyusi’s Project for the Translation of Arabic (PROTA),
Michelle Hartman
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source