Results 1 to 10 of about 436,469 (231)

Early risk assessment for COVID-19 patients from emergency department data using machine learning

Scientific Reports, 2021
Since its emergence in late 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic with more than 55 million reported cases and 1.3 million estimated deaths worldwide.
Frank S. Heldt, Marcela P. Vizcaychipi, Sophie Peacock, Mattia Cinelli, Lachlan McLachlan, Fernando Andreotti, Stojan Jovanović, Robert Dürichen, Nadezda Lipunova, Robert A. Fletcher, Anne Hancock, Alex McCarthy, Richard A. Pointon, Alexander Brown, James Eaton, Roberto Liddi, Lucy Mackillop, Lionel Tarassenko, Rabia T. Khan   +18 more
doaj   +1 more source

Defining the therapeutic reference range for cariprazine

European Psychiatry, 2023
Introduction According to the Consensus Guideline, the “therapeutic reference range” (TRR) defines ranges of drug blood concentrations that specify a lower limit below which a drug-induced therapeutic response is unlikely to occur and an upper limit ...
M. Kapás, A. Horváth, D. Djuric, R. Csehi, Á. Barabássy   +4 more
doaj   +1 more source

Pertussis Toxin-sensitive Activation of Phospholipase C by the C5a and fMet-Leu-Phe Receptors [PDF]

, 1996
Signal transduction pathways that mediate C5a and fMet-Leu-Phe (fMLP)-induced pertussis toxin (PTx)-sensitive activation of phospholipase C (PLC) have been investigated using a cotransfection assay system in COS-7 cells.
Jiang, Huiping, Kuang, Yanan, Simon, Melvin I., Smrcka, Alan, Wu, Dianqing, Wu, Yanping   +5 more
core   +1 more source

PLC

, 2021
What do PLCs do?
openaire   +2 more sources

Similarity-based prediction of ejection fraction in heart failure patients

Informatics in Medicine Unlocked, 2022
Biomedical research is increasingly employing real world evidence (RWE) to foster discoveries of novel clinical phenotypes and to better characterize long term effect of medical treatments.
Jamie Wallis, Andres Azqueta-Gavaldon, Thanusha Ananthakumar, Robert Dürichen, Luca Albergante   +4 more
doaj   +1 more source

A multicentre, efficacy and safety study of methotrexate to increase response rates in patients with uncontrolled gout receiving pegloticase (MIRROR): 12-month efficacy, safety, immunogenicity, and pharmacokinetic findings during long-term extension of an open-label study

Arthritis Research & Therapy, 2022
Background Publications suggest immunomodulation co-therapy improves responder rates in uncontrolled/refractory gout patients undergoing pegloticase treatment.
John K. Botson, John R. P. Tesser, Ralph Bennett, Howard M. Kenney, Paul M. Peloso, Katie Obermeyer, Yang Song, Brian LaMoreaux, Lin Zhao, Yan Xin, Jason Chamberlain, Srini Ramanathan, Michael E. Weinblatt, Jeff Peterson   +13 more
doaj   +1 more source

Large UK retailers' initiatives to reduce consumers' emissions: a systematic assessment [PDF]

, 2017
In the interest of climate change mitigation, policy makers, businesses and non-governmental organisations have devised initiatives designed to reduce in-use emissions whilst, at the same time, the number of energy-consuming products in homes, and ...
Abrahamse, Adams, Alliance Boots, Alliance Boots, Alliance Boots, Alliance Boots, Alliance Boots, Alliance Boots, Alliance Boots, Anne Tallontire, ASDA., B&Q, B&Q, B&Q, B&Q, Berry, Blaszczyk, Borin, Bratt, British Retail Consortium, Broeckelmann, Broman, Brown, Carrero, Charter, Chitnis, Chitnis, Chu, Cochoy, Darnton, DEFRA., Department For Energy and Climate Change, Department of Energy and Climate Change, Department of Energy and Climate Change, Dholakia, Dolan, Dreborg, Elizabeth Morgan, Forum for the Future, Foxon, Gabriel, Global Reporting Initiative, Gouldson, Gómez, Hallstedt, Heinzle, Herzig, Holmberg, Holmberg, Horne, Huber, Inderst, Jackson, John Lewis Partnership, John Lewis Partnership, John Lewis Partnership, John Lewis Partnership, John Lewis Partnership, John Lewis Partnership, John Lewis Partnership, John Lewis Partnership, John Lewis Partnership, John Lewis Partnership, John Lewis Partnership, Jones, Jones, Kingfisher Plc, Kingfisher Plc, Kingfisher Plc, Kingfisher Plc, Kingfisher Plc, Kingfisher Plc, Kingfisher Plc, Kingfisher Plc, Kolk, Kök, Löfgren, Marks, Marks, Marks, Marks, Marks, Marks, Marks, Marks, Marks, Marks, Marsden, McKinnon, Mintel, Mintel, Missimer, Morrisons, Morrisons, Morrisons, Morrisons, Morrisons, Morrisons, Morrisons, Nicholls, Ny, OECD, Owen, Robèrt, Robèrt, Sainsbury plc, Sainsbury Plc, Sainsbury Plc, Sainsbury Plc, Sainsbury Plc, Sainsbury Plc, Sainsbury Plc, Shankar, Shove, Smith, Southerton, Southerton, Spaargaren, Spiekermann, Stafford, Stewart, TESCO, Tesco plc, Tesco Plc, Tesco Plc, Tesco Plc, Tesco Plc, Tesco Plc, Tesco Plc, Tesco Plc, Thaler, The Carbon Trust, The Climate Group, The Climate Group, Timothy J. Foxon, Trentmann, Tukker, Upham, Upham, Vakratsas, Van Bavel, Van Herpen, Van Nierop, Walmart, Walmart, Walmart, Walmart, Walmart, Walmart   +148 more
core   +1 more source

Risk factors for exacerbations and pneumonia in patients with chronic obstructive pulmonary disease: a pooled analysis

Respiratory Research, 2020
Background Patients with chronic obstructive pulmonary disease (COPD) are at risk of exacerbations and pneumonia; how the risk factors interact is unclear.
Benjamin F. Hartley, Neil C. Barnes, Sally Lettis, Chris H. Compton, Alberto Papi, Paul Jones   +5 more
doaj   +1 more source

Ezrin-related phosphoinositide pathway modifies RhoA and Rac1 in human osteosarcoma cell lines [PDF]

, 2015
Selected Phosphoinositide-specific Phospholipase C (PI-PLC) enzymes occupy the convergence point of the broad range of pathways that promote Rho and Ras GTPase mediated signalling, which also regulate the activation of ezrin, a member of the ezrin ...
DELLA ROCCA, Carlo, Leopizzi, Martina, LO VASCO, VINCENZA RITA   +2 more
core   +1 more source

Color Octet Contribution to $J/\psi$ Production at a Photon Linear Collider [PDF]

, 1998
We investigate $J/\psi$ production at a Photon Linear Collider (PLC) in the framework of NRQCD factorization approach. It was shown that color octet contribution is dominating in charmonium production at PLC.
A Tkabladze, Beneke, Bodwin, Borden, Braaten, Cacciari, Cho, Fleming, G Japaridze, Gingburg, Ginzburg, Glück, Ko, Krämer, Lepage, Ma, Telnov, Teryaev, Vänttinen, Witten, Éboli   +20 more
core   +3 more sources