Results 21 to 30 of about 194,741 (300)

Extracorporeal Membrane Oxygenation (ECMO) and hospital economics

The Journal of ExtraCorporeal Technology
Background: Extracorporeal membrane oxygenation (ECMO) is a powerful, life-prolonging technology, but is resource-intensive. Methods: This retrospective analysis utilized Medicare Fee-for-Service (FFS) inpatient data (October 2019–December 2022) to ...
Ratiu Anna, Linick Julie A., Oyugi Angelica, Williams Jennifer, Wherry Kael, Klavetter Eric   +5 more
doaj   +1 more source

Snus: a compelling harm reduction alternative to cigarettes

Harm Reduction Journal, 2019
Snus is an oral smokeless tobacco product which is usually placed behind the upper lip, either in a loose form or in portioned sachets, and is primarily used in Sweden and Norway.
Elizabeth Clarke, Keith Thompson, Sarah Weaver, Joseph Thompson, Grant O’Connell   +4 more
doaj   +1 more source

Bioequivalence study of a new fixed-dose combination of valsartan and indapamide (modified-release tablets) versus concomitant administration of the respective reference single-ingredient products

Рациональная фармакотерапия в кардиологии
Aim. Тo evaluate the bioequivalence of Valsartan + Indapamide 160 mg + 1.5 mg modified release tablets developed by Gedeon Richter Polska Sp. z o. o. (Poland) compared to the reference products Diovan® (Siegfried Barbera S.L.
K. Tóth, M. A. García, B. D. Szmodics, A. Orosz, P. L. Herman, E. N. Balogh, B. I. Forgács, G. Magyar, E. Cseh, E. A. Pravkina   +9 more
doaj   +1 more source

Atlas of plasma NMR biomarkers for health and disease in 118,461 individuals from the UK Biobank

Nature Communications, 2023
The authors report a systematic analyses of blood biomarkers for metabolism against the whole spectrum of diseases in 100,000 individuals and reveals a prominent role of numerous metabolic biomarkers as risk markers beyond heart disease and diabetes.
Heli Julkunen, Anna Cichońska, Mika Tiainen, Harri Koskela, Kristian Nybo, Valtteri Mäkelä, Jussi Nokso-Koivisto, Kati Kristiansson, Markus Perola, Veikko Salomaa, Pekka Jousilahti, Annamari Lundqvist, Antti J. Kangas, Pasi Soininen, Jeffrey C. Barrett, Peter Würtz   +15 more
doaj   +1 more source

Immunogenicity of mRNA-1273 and BNT162b2 in Immunocompromised Patients: Systematic Review and Meta-analysis Using GRADE

Infectious Diseases and Therapy
Introduction Immunocompromised (IC) patients mount poor immune responses to vaccination. Higher-dose coronavirus disease 2019 (COVID-19) vaccines may offer increased immunogenicity.
Sushma Kavikondala, Katrin Haeussler, Xuan Wang, Anne Spellman, Mary T. Bausch-Jurken, Pawana Sharma, Mohammadreza Amiri, Anna Krivelyova, Sonam Vats, Maria Nassim, Nitendra Kumar, Nicolas Van de Velde   +11 more
doaj   +1 more source

Does scrolling affect measurement equivalence of electronic patient-reported outcome measures (ePROM)? Results of a quantitative equivalence study

Journal of Patient-Reported Outcomes, 2021
Background Scrolling is a perceived barrier in the use of bring your own device (BYOD) to capture electronic patient reported outcomes (ePROs). This study explored the impact of scrolling on the measurement equivalence of electronic patient-reported ...
Saeid Shahraz, Tan P. Pham, Marc Gibson, Marie De La Cruz, Munther Baara, Sachin Karnik, Christopher Dell, Sheryl Pease, Suyash Nigam, Joseph C. Cappelleri, Craig Lipset, Patrick Zornow, Jeff Lee, Bill Byrom   +13 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Lack of Clinically Meaningful Effect of Cariprazine on the Pharmacokinetics of a Combined Oral Contraceptive

Neurology and Therapy
Introduction Cariprazine (CAR) is a potent dopamine receptor partial agonist antipsychotic approved by the EMA and the FDA. To address the uncertainty regarding the effectiveness of hormonal contraceptives during CAR co-administration and whether a ...
Márta Erzsébet Rosa, Zoltán Juhász, Gabriella Pásztor Mészáros, Gabriella Magyar, Judit Harsányi, Balázs Szatmári, Zoltán Hujber, Máté Szabó, Margit Kapás   +8 more
doaj   +1 more source

Methods of Evaluating of Sensory Assessors – Part 1

Kvasný průmysl, 2018
The precission and repeatability of sensory analysis is infl uenced by a number of physiological, psychological and genetic factors. These can be largely eliminated by appropriate selection of the assessors through their regular evaluation.
Pavel Čejka, Jana Olšovská, Karel Štěrba, Martin Slabý, Tomáš Vrzal   +4 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source