Results 41 to 50 of about 436,568 (329)

Can medicines development improve outcomes in asthma and chronic obstructive pulmonary disease management by driving effectiveness?

Respiratory Research, 2019
Despite the availability of treatment guidelines and inhaled medications for asthma and chronic obstructive pulmonary disease (COPD), much remains to be done to lessen the burden of these respiratory diseases for patients.
David A. Leather, Louisa Yates, Henrik Svedsater, Loretta Jacques, Susan Collier, Danielle Powell, Rupert Jones   +6 more
doaj   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Assessing the economic impact of obesity and overweight on employers: identifying opportunities to improve work force health and well-being

Nutrition & Diabetes
Background and objectives Obesity is a major public health issue, significantly affecting national and individual health and economic well-being. This study quantifies the economic impact of excess body weight on employers and employees in 2023, offering
Timothy M. Dall, Tanvi Sapra, Zachary Natale, Tia Livingston, Fang Chen   +4 more
doaj   +1 more source

EVALUATION OF PLC PROGRAMME PROVISION. ESRI RESEARCH SERIES NUMBER 61 JANUARY 2018 [PDF]

, 2018
Post-Leaving Certificate (PLC) courses represent the largest component of full-time further education and training (FET) provision in Ireland, with over 32,000 learners enrolled in such courses in 2015–2016.
Bergin, Adele, Kelly, Elish, McCoy, Selina, McGuinness, Seamus, Smyth, Emer, Watson, Dorothy, Whelan, Adele   +6 more
core  

Learning-aided Stochastic Network Optimization with Imperfect State Prediction

, 2018
We investigate the problem of stochastic network optimization in the presence of imperfect state prediction and non-stationarity. Based on a novel distribution-accuracy curve prediction model, we develop the predictive learning-aided control (PLC ...
Ananthanarayanan G., Bertsekas D. P., Tadrous J., Xu K., Zhao S.   +4 more
core   +1 more source

The Renal Activity Index for Lupus Identifies Active Renal Disease and Treatment Response in Adult Patients With Systemic Lupus Erythematosus and Lupus Nephritis

Arthritis Care &Research, EarlyView.
Objective We evaluated the ability of the Renal Activity Index for Lupus (RAIL) to discriminate active lupus nephritis (LN) in adult patients with active systemic lupus erythematosus (SLE) and differentiate LN treatment response. Methods Urine samples from adults with biopsy‐proven active class III and IV LN from TULIP‐LN (active LN group ...
Hermine I. Brunner, Ellen M. Cody, Prasad Devarajan, Bin Huang, Chen Chen, Dominic Sinibaldi, Madhu Ramaswamy, Jacob Knagenhjelm, Frederick Jones, Philip Z. Brohawn, Raj Tummala, Catharina Lindholm, Wendy I. White   +12 more
wiley   +1 more source

Scaling Behaviour and Complexity of the Portevin-Le Chatelier Effect

, 2006
The plastic deformation of dilute alloys is often accompanied by plastic instabilities due to dynamic strain aging and dislocation interaction. The repeated breakaway of dislocations from and their recapture by solute atoms leads to stress serrations and
A. SARKAR, Baird J. D., Brindley B. J., Cottrell A. H., Cottrell A. H., Gnedenko B. V., Le Chatelier F., Mandelbort B. B., Masson A. M., P. BARAT, Pincus S. M., Pink E., Portevin A., Richman J. S., Savart F.   +14 more
core   +1 more source

Interaction between Molten Al‐Killed Mn–B Steel and Carbon‐Bonded MgO Refractories Based on Recyclates

Advanced Engineering Materials, EarlyView.
High‐temperature interactions between low‐sulfur Al‐killed Mn–B steel and MgO–C refractories (0 and 50 wt% recyclates) are studied via finger immersion tests (1600 °C). Surface‐active elements influence infiltration. MgO/CaS layer forms, along with spinel and calcium silicate.
Matheus Roberto Bellé, Lukas Neubert, Anton Yehorov, Till M. J. Stadtmüller, Christos G. Aneziris, Olena Volkova   +5 more
wiley   +1 more source

Development and validation of blood-based diagnostic biomarkers for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) using EpiSwitch® 3-dimensional genomic regulatory immuno-genetic profiling

Journal of Translational Medicine
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating, multifactorial disorder characterised by profound fatigue, post-exertional malaise, cognitive impairments, and autonomic dysfunction. Despite its significant impact on quality
Ewan Hunter, Heba Alshaker, Oliver Bundock, Cicely Weston, Shekinah Bautista, Abel Gebregzabhar, Anya Virdi, Joseph Croxford, Ann Dring, Ryan Powell, Dominik Vugrinec, Caroline Kingdon, Carol Wilson, Sarah Dowrick, Jayne Green, Alexandre Akoulitchev, Dmitri Pchejetski   +16 more
doaj   +1 more source

Channel characterisation of cooperative relaying power line communication systems [PDF]

, 2016
© 2016 IEEE. Power line communication (PLC) technology offers a promising platform for numerous communication applications. The power lines however can significantly attenuate communication signals operating in high frequency band. For this reason, multi-
Adebisi, Bamidele, Ikpehai, Augustine, Rabie, Khaled M, Rozman, Matjaz   +3 more
core   +2 more sources