Results 81 to 90 of about 169,013 (248)

Trastuzumab Emtansine for the Treatment of HER-2 Positive Carcinoma Ex-pleomorphic Adenoma Metastatic to the Brain: A Case Report

Frontiers in Oncology, 2018
Background: Carcinoma Ex-pleomorphic adenoma is a malignant transformation of the common benign neoplasm of the salivary glands, “pleomorphic adenoma.” Only two cases were ever reported with brain metastases, with absence of good evidence guiding ...
Ihab Hassanieh, Ihab Hassanieh, Lara Hilal, Lara Hilal, Karine A. Al Feghali, Karine A. Al Feghali, Ibrahim Khalifeh, Bassem Youssef, Bassem Youssef   +8 more
doaj   +1 more source

Juvenile cellular pleomorphic adenoma [PDF]

BMJ Case Reports, 2013
Salivary gland tumours are rare in children and when they do arise, they preferentially affect major salivary glands with sporadic incidence in minor salivary glands. The mucosa of the cheek is an uncommon site of occurrence for intraoral pleomorphic adenoma and most of these cases have been reported in adults.
Anuradha, Ananthaneni, Suresh Babu, Undavalli   +1 more
openaire   +2 more sources

Clinicopathological effect of PLAG1 fusion genes in pleomorphic adenoma and carcinoma ex pleomorphic adenoma with special emphasis on histological features

Histopathology, 2018
Pleomorphic adenoma gene 1 (PLAG1) rearrangement is well known in pleomorphic adenoma (PA), which is histologically characterised by admixed epithelial and mesenchymal components. Multiple fusion variants of PLAG1 and HMGA2 have been reported; currently,
Miki Asahina, Tsuyoshi Saito, T. Hayashi, Y. Fukumura, K. Mitani, T. Yao   +5 more
semanticscholar   +1 more source

Extracapsular Parotidectomy: A Safe Alternative to Partial Superficial Parotidectomy in Properly Selected Patients

OTO Open, Volume 10, Issue 1, January-March 2026.
Abstract Objective Partial superficial parotidectomy (PSP) is the surgical option of choice for treating benign tumors in the superficial lobe of the parotid gland. The less invasive extracapsular parotidectomy (ECP) technique was previously described.
Mazin Merdad, Mohammed Njoom
wiley   +1 more source

Pleomorphic adenoma involving soft tissue overlying the anterior border of ramus of the mandible: A rare ectopic presentation

Journal of Oral Biology and Craniofacial Research, 2016
Ectopic pleomorphic adenoma is a rare presentation in sites other than major and minor salivary glands. In literature, cases of pleomorphic adenoma in the soft tissue of the neck, skin of the external auditory canal, subcutaneous layer of nose, and lymph
Naresh Kumar Sharma, Akhilesh Kumar Singh, Arun Pandey, Vishal Verma   +3 more
doaj   +1 more source

Squamous Metaplasia in Pleomorphic Adenoma: A Diagnostic and Prognostic Enigma

Journal of Pathology and Translational Medicine, 2018
Pleomorphic adenoma (PA) is the most common benign salivary gland tumor. Histologically, squamous metaplasia has been reported in PA, but has rarely been documented as being extensive enough to cause significant misdiagnosis.
Swati Sharma, M. Mehendiratta, Nivedita Chaudhary, V. Gupta, Maulshree Kohli, Anjana Arora   +5 more
semanticscholar   +1 more source

Recent developments in eosinophilic renal neoplasms: what's new, true and important?

Histopathology, Volume 88, Issue 1, Page 166-192, January 2026.
Recent developments and acquired knowledge on newer renal entities with eosinophilic cytoplasm opened insights into the clinical, pathological, immunohistochemical, molecular, epidemiological aspects, and the prognosis of these entities. We emphasize the role of routine morphology, aided by appropriate and select immunohistochemistry, as essential keys
Kiril Trpkov, Farshid Siadat, Rola Saleeb   +2 more
wiley   +1 more source

Chromosome Translocations, Gene Fusions, and Their Molecular Consequences in Pleomorphic Salivary Gland Adenomas [PDF]

, 2022
Göran Stenman, André Fehr, Alena Skálová, Vincent Vander Poorten, Henrik Hellquist, Lauge Hjorth Mikkelsen, Nabil F. Saba, Orlando Guntinas‐Lichius, Carlos M. Chiesa‐Estomba, Mattias K. Andersson, Alfio Ferlito   +10 more
openalex   +1 more source

PLAGL1 overexpression exacerbates type 1 diabetes by inducing β‐cell apoptosis via oxidative stress‐dependent dual DNA damage and cGAS/STING pathway activation

Journal of Diabetes Investigation, Volume 17, Issue 1, Page 12-24, January 2026.
ABSTRACT Background Type 1 diabetes mellitus (T1DM) arises from autoimmune destruction of pancreatic β‐cells. Pleomorphic adenoma gene‐like 1 (PLAGL1) overexpression has been linked to β‐cell apoptosis, but molecular mechanisms remain incompletely understood.
Cheng Li, Lingyan Qiao, Juan Ge, Sicui Hu, Hongxiu Yang, Conghui Hu, Tang Li   +6 more
wiley   +1 more source

Clinicopathological Profile of Intraosseous Adenoid Cystic Carcinoma of the Jaws: A Systematic Review

Journal of Oral Pathology &Medicine, Volume 55, Issue 1, Page 32-41, January 2026.
ABSTRACT Objectives We aimed to evaluate the clinicopathological features, survival rate, and potential prognostic markers of the jaws' primary intraosseous adenoid cystic carcinoma (PIACC). Materials and Methods MEDLINE/PubMed, Scopus, and Embase searches were performed with the keywords “adenoid cystic carcinoma,” and “jaw,” or “maxilla,” or ...
Luccas Lavareze, João Figueira Scarini, Reydson Alcides de Lima‐Souza, Talita de Carvalho Kimura, Rogério de Oliveira Gondak, Erika Said Abu Egal, Albina Altemani, Fernanda Viviane Mariano   +7 more
wiley   +1 more source