Results 91 to 100 of about 31,642 (278)

The Evolution in Understanding the Physiological Causes of Dyspnoea in Large Hiatal Herniation: A Narrative Review

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background The symptomatology of large hiatus hernia (LHH) has been historically poorly understood, with cardiorespiratory symptoms caused by LHH being underappreciated by clinicians. This study reports on the mechanisms of dyspnoea in LHH through a historical review of symptoms and evolved physiological literature, discussing likely causation.
Arunan Mahendravarman, Fienne Cordeschi, Gregory Leighton Falk   +2 more
wiley   +1 more source

The pattern of methacholine responsiveness in mice is dependent on antigen challenge dose [PDF]

, 2004
Background Considerable variation exists in the protocols used to induce hyperresponsiveness in murine models of allergic sensitisation. We examined the effect of varying the number of antigen exposures at challenge on the development of methacholine ...
Sly, P.D., Stumbles, P.A., Zosky, G.R., von Garnier, C., Holt, P.G., Turner, D.J.   +5 more
core   +1 more source

Chronic intermittent hypoxia‐mediated cognitive dysfunction in ovariectomized rats

Experimental Physiology
Obstructive sleep apnoea (OSA) is a prevalent cardiorespiratory disorder associated with significant neurocognitive consequences. Despite the higher prevalence of OSA in men, there is a strong association between OSA and Alzheimer's disease (AD), which ...
Emily C. Cheung, Joan B. Escobar, Bridget R. Alber, Caitlin Ribeiro, Ishan Abdullah, Grant Kowalik, Jeannette Rodriguez, Grey Harral, Makeda Melkie, Aman Gill, John T. Ketzenberger, John Bethea, Vsevolod Y Polotsky, Vivek Jain, Kathryn Schunke, Matthew W. Kay, David Mendelowitz   +16 more
doaj   +1 more source

Perfusion index as a predictor of hypotension following propofol induction - A prospective observational study

Indian Journal of Anaesthesia, 2017
Background and Aims: Hypotension during propofol induction is a common problem. Perfusion index (PI), an indicator of systemic vascular resistance, is said to be predictive of hypotension following subarachnoid block.
Sripada G Mehandale, Preethi Rajasekhar
doaj   +1 more source

Physical Activity Profile of School‐Aged Children Born Very Preterm and Its Association With Sleep

Acta Paediatrica, EarlyView.
ABSTRACT Aim To describe the association between different physical activity and sleep parameters in school‐aged children born very preterm. Methods A cross‐sectional analysis was done in a cohort of 6‐ to 10‐year‐old children born at < 32 weeks' gestation at the Department of Neonatology, University of Tübingen, Germany.
Maham Hassan, Saskia Koller, Annkathrin Gies, Axel R. Franz, Johanna Catharina Brückner, Vadim Förster, Christian F. Poets, Christoph Randler, Cornelia Wiechers, Mirja Quante   +9 more
wiley   +1 more source

Optoelectronic plethysmography in clinical practice and research: a review [PDF]

, 2017
Background: Optoelectronic plethysmography (OEP) is a non-invasive motion capture method to measure chest wall movements and estimate lung volumes.
Silvestri, Sergio, Saccomandi P, Emiliano Schena, Miccinilli, Sandra, Michelangelo Morrone, Samantha L Winter, Samantha Winter, Massaroni, Carlo, John W Dickinson, Elena Carraro, Saccomandi, Paola, Dickinson, John W., Carraro, Elena, Vianello, Andrea, Silvia Sterzi, Paola Saccomandi, Carlo Massaroni, Levai, Irisz, Irisz K. Levai, Andrea Vianello, Sergio Silvestri, Sterzi, Silvia, Schena, Emiliano, Irisz Levai, Winter, Samantha, Morrone, Michelangelo, Sandra Miccinilli, Levai, Irisz K., Winter, Samantha L., John W. Dickinson   +29 more
core   +1 more source

Prolonged ictal and post‐ictal central apnea in an epileptic seizure

Epileptic Disorders, EarlyView.
Wei Zhao, Alena Berkhamova, Rabeha Noor, Abdulrahman Alwaki, Elli Allen   +4 more
wiley   +1 more source

Therapeutic targeting of bleomycin‐induced pulmonary fibrosis by human bone marrow mesenchymal stem cell‐derived extracellular vesicles and/or pirfenidone: Impact of sex in mature adult mice

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with limited therapeutic options. This study compared the therapeutic effects of bone marrow mesenchymal stem cell‐derived extracellular vesicles (BM‐MSC‐EVs) with an IPF treatment, pirfenidone (PFD), in mature adult mice with established pulmonary ...
Jennie S. Charoenphannathon, Simon G. Royce, Yasmin Higham, Jane E. Bourke, Chrishan S. Samuel   +4 more
wiley   +1 more source

Cannabinoid CB1 allosteric ligands suppress inflammatory pain in male mice without tolerance, motor impairment, memory deficits or respiratory depression

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Positive allosteric modulators (PAMs) engage sites distinct from the orthosteric CB1 cannabinoid receptor binding site. GAT211, a racemic ligand, contains GAT228 (R) and GAT229 (S) enantiomers. Whether enantiomer‐mediated differences in allosteric activation or positive allosteric modulation translate into differences in
Ifeoluwa D. Solomon, Sumanta Garai, Ganesh A. Thakur, Andrea G. Hohmann   +3 more
wiley   +1 more source

Feasibility and usability of three consecutive nights with self‐applied, home polysomnography

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary In‐laboratory polysomnography, the gold‐standard for diagnosing sleep disorders, is resource‐demanding and not conducive to multiple night evaluations. Ambulatory polysomnography, especially when self‐applied, could be a viable alternative. This study aimed to assess the feasibility and reliability of self‐applied polysomnography over three ...
Dimitri Ferretti, Anna S. Islind, Kristín A. Ólafsdóttir, Sigridur Sigurdardottir, Kamilla R. Jóhannsdóttir, Jan Hedner, Ludger Grote, Erna Sif Arnardottir   +7 more
wiley   +1 more source