Results 41 to 50 of about 34,853 (259)
SDPR–STK38 axis controls the proliferation–differentiation balance in alveolar type II cells
Animal Models and Experimental Medicine, EarlyView.The present study identifies SDPR as a pivotal regulator orchestrating the balance between proliferation and differentiation in alveolar type II (AT2) cells. In SDPR+/+ cells, SDPR binds to and inhibits STK38 activity, thereby sustaining GSK‐3β signaling functionality to promote cyclin D1 degradation and maintain cell cycle homeostasis.
Jie Wang +6 more
wiley +1 more source
Педиатрическая фармакология, 2018 Background. The development of premature infants is slower than that of term ones, often due to nutritional status disorders in preterm infants. Objective.
Tatiana V. Turti +2 more
doaj +1 more source
Pulse arrival time: Measurement and clinical applications
MGM Journal of Medical Sciences, 2022 Pulse arrival time is the time elapsed between the R-wave of electrocardiogram and systolic peak in peripheral pulse obtained by any of the plethysmographic methods.
Chaitali A Deshmukh +3 more
doaj +1 more source
Animal Models and Experimental Medicine, EarlyView.This study develops a reformulated tribromoethanol (TBE) anesthetic using 1,2‐propanediol as a solvent to overcome solvent‐related toxicity. The novel formulation demonstrates, cardiovascular stability, and survival in prolonged protocols. It provides potent, dose‐dependent anesthesia without strain or sex differences.
Xia Li +3 more
wiley +1 more source
Frontiers in Physiology, 2019 ObjectivesThe aim of this study was to evaluate the acute effects of different inspiratory loads and different interfaces on the breathing pattern and activity of the respiratory muscles.MethodsTwenty healthy adults were recruited and assigned to two ...
Jéssica Danielle Medeiros da Fonsêca +8 more
doaj +1 more source
An Investigation of Sleep Macro‐ and Microarchitecture by APOE Genotype
Annals of Neurology, EarlyView.Objectives Apolipoprotein E ε4 (APOE ε4), a robust genetic risk factor for Alzheimer's disease (AD) is associated with functional connectivity deficits and amyloid pathology in brain regions involved in sleep regulation. Thus, alterations in sleep architecture may be one pathway through which ε4 contributes to Alzheimer's disease vulnerability. However,
Gawon Cho +6 more
wiley +1 more source
Three‐dimensional geometric morphometric analysis of diaphragmatic dome motion in COPD patients
The Anatomical Record, EarlyView.Abstract Diaphragmatic dysfunction is a hallmark of chronic obstructive pulmonary disease (COPD), especially in emphysema, where hyperinflation alters diaphragm geometry and impairs inspiratory mechanics. However, quantitative three‐dimensional (3D) assessments of diaphragmatic dome shape and motion across COPD phenotypes are limited.
José M. López‐Rey +5 more
wiley +1 more source
Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury
British Journal of Clinical Pharmacology, EarlyView.Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra +8 more
wiley +1 more source
Modified Barometric Plethysmography.
, 2016 Photograph of plethysmography set up for ventilatory function analysis. (A) Animal chamber; (B) Reference chamber; (C) Transducer; (D) Thermometer; (E) Polygraph machine; (F) Gas mixture; (G) Flow meter.
Milind R. Chaudhari (848011) +2 more
core +1 more source
Venous occlusion plethysmography in patients with post-thrombotic venous claudication [PDF]
, 2013 ObjectivePost-thrombotic venous claudication is a serious condition that may be treated with iliac vein stenting or open surgery, and there is a need for hemodynamic tests in the preoperative evaluation.
Rosfors, Stefan +3 more
core +1 more source