Results 51 to 60 of about 34,853 (259)

Safety and pharmacokinetics of mosliciguat, a new, inhaled soluble guanylate cyclase activator, in healthy adult subjects

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mosliciguat (BAY 1237592), the first soluble guanylate cyclase (sGC) activator in a dry powder inhaler (DPI), could potentially treat pulmonary hypertension with a more targeted delivery than systemic sGC stimulators. We report safety and tolerability of mosliciguat in healthy men.
Johannes Nagelschmitz, Soundos Saleh, Sandra Ligges, Melanie Seidel‐Greven, Eva Becker‐Pelster, Sylvia M. Nikkho, Stefanie Boxnick, Wolfgang Timmer   +7 more
wiley   +1 more source

Opto-electronic plethysmography in intensive care patients

, 2000
We used optoelectronic plethysmography to study 11 normal subjects during quiet and deep breathing, six sedated and paralyzed patients with acute lung injury and acute respiratory distress syndrome (ALI/ARDS) receiving continuous positive pressure ...
CHIUMELLO D., ALIVERTI, ANDREA, P. Pelosi, R. Dellacá, A. Aliverti, PEDOTTI, ANTONIO, GATTINONI L., L. Gattinoni, D. Chiumello, A. Pedotti, DELLACA', RAFFAELE, PELOSI P.   +11 more
core   +1 more source

Revisiting the concept that interictal implies asymptomatic: Pulse wave amplitude drops uncover autonomic responses during generalized paroxysmal fast activities

Epilepsia, EarlyView.
Abstract Objective Interictal electroencephalographic (EEG) activities are generally considered asymptomatic. Pulse wave amplitude drop (PWAD) is a marker of autonomic nervous system (ANS) reactivity linked to cardiovascular risk. Generalized paroxysmal fast activity (GPFA) is a major EEG pattern in different epileptic conditions.
Julie Lévi‐Strauss, Valerio Frazzini, Claude Adam, Isabelle Gourfinkel‐An, Sophie Dupont, Vincent Navarro, Vi‐Huong Nguyen‐Michel   +6 more
wiley   +1 more source

Electromagnetic sensor for measuring the dielectric permeability of materials

Вісник Харківського національногоуніверситету імені В.Н. Каразіна. Серія: Радіофізика та електроніка, 2020
Relevance: Problems of control and determination of electrophysical parameters of materials of different physical nature are relevant in terms of the development of express methods of analysis of substances in various fields of science and technology, in
Ye. A. Antonenko, V. A. Kozheshkurt, D. A. Shtoda, V. A. Katrich, A. I. Bozhkov   +4 more
doaj   +1 more source

Detection of focal impaired awareness seizures using a biometric shirt

Epilepsia Open, EarlyView.
Abstract Objective In recent years, seizure detection using wearable technology has gained significant attention in research. Most studies, however, have focused on detecting generalized or focal to bilateral tonic–clonic seizures. This study evaluates the feasibility of using a biometric shirt to detect focal impaired awareness seizures (FIAS) by ...
Jérôme St‐Jean, Oumayma Gharbi, Dènahin Hinnoutondji Toffa, Thi Phuoc Yen Tran, Manon Robert, Dang Khoa Nguyen, Elie Bou Assi   +6 more
wiley   +1 more source

Chemogenetic stimulation of phrenic motor output and diaphragm activity

eLife
Impaired respiratory motor output contributes to morbidity and mortality in many neurodegenerative diseases and neurologic injuries. We investigated if expressing designer receptors exclusively activated by designer drugs (DREADDs) in the mid-cervical ...
Ethan S Benevides, Prajwal P Thakre, Sabhya Rana, Michael D Sunshine, Victoria N Jensen, Karim Oweiss, David D Fuller   +6 more
doaj   +1 more source

Investigation of the Methodology of Specific Airway Resistance Measurements in COPD

International Journal of COPD, 2023
James Dean,1,2,* Dave Singh1,2,* 1Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester University NHS Foundation Trust ...
Dean J, Singh D
doaj  

Targeting eEF1A1 With Baicalein to Block eEF1A1/Prdx4 Interaction for Treating Sepsis‐Mediated Lung Injury

Exploration, EarlyView.
Targeting eEF1A1 with baicalein disrupts the eEF1A1‐Prdx4 interaction to prevent RNF14‐mediated ubiquitination and degradation of Prdx4. This stabilizes Prdx4 to suppress NF‐κB, thereby alleviating sepsis‐induced acute lung injury. ABSTRACT Sepsis is a systemic inflammatory response syndrome triggered by an uncontrolled host response to infection ...
Jing Chang, Hui‐Lin Zhang, Qi‐Meng Zhu, Si‐Wen Hui, Xin‐Rong Xu, Mahmood Brobbey Oppong, Yan‐Li Feng, Juan Zhang, Cheng‐Peng Sun, Feng Qiu   +9 more
wiley   +1 more source

Pulmonary plethysmography

, 2014
Lung (or pulmonary) plethysmography is a test used to measure how much air you can hold in your lungs. Lung plethysmography helps healthcare providers assess patients with lung diseases, which are often associated with a decrease in total lung capacity ...
Onwujekwe, Udodi, Gerasimchuk, Nina, Ogunyemi, Opeyemi Oluwafunmilayo   +2 more
core   +1 more source

Wearable Belt With Built-In Textile Electrodes for Cardio—Respiratory Monitoring

Sensors, 2020
Unobtrusive and continuous monitoring of vital signs is becoming more and more important both for patient monitoring in the home environment and for sports activity tracking.
Emanuele Piuzzi, Stefano Pisa, Erika Pittella, Luca Podestà, Silvia Sangiovanni   +4 more
doaj   +1 more source