Results 61 to 70 of about 129,636 (342)

Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho‐Epithelial Cells by Modulating Eicosanoid Lipid Signaling

open access: yesAdvanced Science, EarlyView.
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta   +14 more
wiley   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

open access: yesAdvanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu   +11 more
wiley   +1 more source

Microgel‐Based Hierarchical Porous Hydrogel Patch with Adhesion and Resilience for Myocardial Infarction

open access: yesAdvanced Science, EarlyView.
This study develops a hierarchically porous hydrogel patch strategy (HPMP), based on gas‐shearing microfluidics and an aqueous two‐phase system to fabricate porous microgels as microgel‐based bioinks. The porous microgels with controllable porous structure exhibit excellent cellular behavior.
Ziyang Liu   +13 more
wiley   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu   +7 more
wiley   +1 more source

A new species of Cydistomyia (Diptera, Tabanidae) from Papua New Guinea [PDF]

open access: yes, 1999
A new species, Cydistomyia kamialiensis, is described from specimens collected in the Kamiali Wildlife Management Area of Morobe Province, Papua New ...
Goodwin, James T.
core  

Blood vessels and their construction in the cavities of pulmonary tuberculosis [PDF]

open access: yes, 1958
First of all, we investigated the origin, the construction and distribution of the bronchial arteries and veins in adult rabbits, and then observed various changes of the blood vessels in experimental cavities and caseous foci and also studied the ...
Hiraki, Kiyoshi, Takata, Jun-nosuke
core   +1 more source

Impact of Combined Resection of the Pancreas on Long‐Term Survival in Gastric Cancer

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Short‐term and long‐term results of patients underwent conbined pancreatectomy was investigated in 64 patients with gastric cancer. R1 resection and postoperative intraabdominal infectious complications were identified as independent prognostic factors.
Taku Hattori   +8 more
wiley   +1 more source

Idiopathic pleuroparenchymal fibroelastosis: a rare case report

open access: yesPAMJ Clinical Medicine, 2020
Idiopathic pleuroparenchymal fibroelastosis (IPPFE) is a rare clinical-pathologic entity characterized by fibrotic thickening of the pleural and subpleural parenchyma predominantly in the upper lobes. The clinical course of the disease is progressive and
Hajar Hamri   +5 more
doaj   +1 more source

Life History and Laboratory Rearing of \u3ci\u3eCorythucha Juglandis\u3c/i\u3e (Hemiptera: Tingidae) With Descriptions of Immature Stages [PDF]

open access: yes, 2017
The life history of Corythucha juglandis was investigated in Jackson and Alexander counties. Illinois. August 1981-December 1985 and the immature stages were described.
McPherson, J. E, Vogt, T. E
core   +2 more sources

Revising Fascial Anatomy With a Focus on the Fusion Fascia in Mesenteric Gastrointestinal Cancer Surgery

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This review critically reassesses our prior hypothesis and proposes a revised anatomical model of the fusion fascia that is broadly applicable to GI cancer surgeries grounded in the principles of mesenteric resection. Our synthesis suggests that the fusion fascia is neither a dense connective tissue membrane nor a remnant of mesothelial fusion, but ...
Hisashi Shinohara   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy