Malignant pleural disease. [PDF]
Malignant pleural disease represents a growing healthcare burden. Malignant pleural effusion affects approximately 1 million people globally per year, causes disabling breathlessness and indicates a shortened life expectancy.
Piggott LM+3 more
europepmc +4 more sources
Imaging of pleural disease. [PDF]
The pleural space is a “potential” anatomical space which is formed of two layers: visceral and parietal. It normally contains a trace of fluid (∼10 mL in each hemithorax).
Hassan M+6 more
europepmc +4 more sources
Diagnostics in Pleural Disease. [PDF]
Pleural disease diagnostics represent a sprawling topic that has enjoyed a renaissance in recent years from humble beginnings. Whilst pleural patients are heterogeneous as a population and in the aetiology of the disease with which they present, we ...
Sundaralingam A, Bedawi EO, Rahman NM.
europepmc +7 more sources
Diagnostic Utility of Pleural Fluid Cell Block versus Pleural Biopsy Collected by Flex-Rigid Pleuroscopy for Malignant Pleural Disease: A Single Center Retrospective Analysis. [PDF]
Some trials recently demonstrated the benefit of targeted treatment for malignant disease; therefore, adequate tissues are needed to detect the targeted gene.
Shion Miyoshi+4 more
doaj +4 more sources
The pleural mesothelium in development and disease [PDF]
The pleural mesothelium, derived from the embryonic mesoderm, is formed by a metabolically active monolayer of cells that blanket the chest wall and lungs on the parietal and visceral surfaces, respectively. The pleura and lungs are formed as a result of
Hitesh Batra, Veena B. Antony
semanticscholar +6 more sources
Management of complex pleural disease in the critically ill patient. [PDF]
Disorders of the pleural space are quite common in the critically ill patient. They are generally associated with the underlying illness. It is sometimes difficult to assess for pleural space disorders in the ICU given the instability of some patients ...
Hu K, Chopra A, Kurman J, Huggins JT.
europepmc +2 more sources
A Phase I Trial of Regional Mesothelin-Targeted CAR T-cell Therapy in Patients with Malignant Pleural Disease, in Combination with the Anti-PD-1 Agent Pembrolizumab. [PDF]
Malignant pleural diseases, comprising metastatic lung and breast cancers and malignant pleural mesothelioma (MPM), are aggressive solid tumors with poor therapeutic response.
Adusumilli PS+29 more
europepmc +2 more sources
Frailty Prevalence and Association with Clinical Outcomes in Interstitial Lung Disease, Asthma, and Pleural Disease [PDF]
Background: Frailty is a syndrome characterised by increased vulnerability to negative outcomes. Interstitial lung disease (ILD), asthma, and pleural disease are leading causes of morbidity and mortality. We aimed to investigate the prevalence and impact
Alessia Verduri+7 more
doaj +2 more sources
Thoracic ultrasound in the modern management of pleural disease. [PDF]
Physician-led thoracic ultrasound (TUS) has substantially changed how respiratory disorders, and in particular pleural diseases, are managed. The use of TUS as a point-of-care test enables the respiratory physician to quickly and accurately diagnose ...
Hassan M, Mercer RM, Rahman NM.
europepmc +2 more sources
IgG4-related pleural disease in a patient with pulmonary adenocarcinoma under durvalumab treatment: a case report. [PDF]
Background Immune checkpoint inhibitors (ICIs) are the standard treatment for non-small cell lung cancer. The unique adverse events that can arise after treatment with ICIs are known as immune-related adverse events (irAE).
Terashima T+7 more
europepmc +2 more sources