Results 51 to 60 of about 148,358 (326)

Visceral Leishmaniasis Masquerading as Drug-Induced Pancytopenia in Lung Cancer Patients

Current Oncology
Maintenance chemotherapy is a standard treatment in patients with non-progressive advance staged IV non-squamous non-small cell lung cancer after induction therapy.
Sophie Laroumagne, Julie Tronchetti, Hervé Dutau, Philippe Astoul   +3 more
doaj   +1 more source

Medical thoracoscopy versus image-guided pleural biopsy for diagnosing pleural diseases

Egyptian Journal of Chest Disease and Tuberculosis, 2018
Background The diagnostic role of medical thoracoscopy and image-guided pleural biopsy in patients with undiagnosed exudative pleural effusion has increased over the last few years.
Emad Ibrahim, Rasha Daabis, Alaa Abdallah, Amr Abdelkerim, Mervat A Ismail   +4 more
doaj   +1 more source

Value of thoracoscopic pictures in predicting the etiology of exudative pleural effusions

Egyptian Journal of Chest Disease and Tuberculosis, 2020
Background With the development of novel devices, medical thoracoscopy (MT) nowadays is very commonly used among pulmonology specialists. It is considered the gold standard not only in the diagnosis but also in the treatment of pleural diseases as it ...
Sameh Embarak, Nagwan A Ismail
doaj   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

Added value of diffusion-weighted MRI in assessment of pleural lesions

The Egyptian Journal of Radiology and Nuclear Medicine, 2021
Background There are many causes of pleural disease including variable benign and malignant etiologies. DWI is a non-enhanced functional MRI technique that allows qualitative and quantitative characterization of tissues based on their water molecules ...
Youssriah Yahia Sabri, Ikram Hamed Mahmoud, Lamis Tarek El-Gendy, Mohamed Raafat Abd El-Mageed, Sally Fouad Tadros   +4 more
doaj   +1 more source

Pathologic diagnosis of malignant mesothelioma: chronological prospect and advent of recommendations and guidelines [PDF]

, 2015
Malignant mesothelioma is rare and difficult to diagnose. Its identification depends upon pathological investigation (cyto-histological assessment and immunohistochemistry) supported by clinical and radiological evidence.
Ascoli, Valeria
core   +2 more sources

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

Estimating past inhalation exposure to asbestos: a tool for risk attribution and disease screening [PDF]

, 2017
Introduction: Late presentation is common in mesothelioma. Reliable assessment of past exposure to asbestos is a necessary first step for risk attribution and for the development of a future screening programme. Such a programme could maximise access
Blyth, Kevin G., Cherrie, John W., McElvenny, Damien   +2 more
core   +1 more source

PTPN2 Inhibition Disrupts Mitochondrial Renewal and Blocks TFRC‐Mediated Mitophagy to Exert Anti‐Tumor Activities in ALK‐Positive Anaplastic Large Cell Lymphoma

Advanced Science, EarlyView.
CRISPR/Cas9 screening reveals PTPN2 as essential for ALK+ ALCL survival. PTPN2 regulates TFRC to promote PINK1‐PRKN mitophagy. Oral PTPN2 inhibitor ABBV‐CLS‐484 disrupts mitochondrial renewal and blocks TFRC‐mediated mitophagy to exert anti‐tumor activities, supporting clinical development for ALK+ ALCL.
Wei‐Ting Wang, Zi‐Wen Duan, Tong‐Yao Xing, Wei Hua, Kai‐Xing Du, Chun‐Yu Shang, Yi‐Fan Wu, Li Wang, Jian‐Yong Li, Rui Gao, Jin‐Hua Liang, Wei Xu   +11 more
wiley   +1 more source

CT in differential diagnosis of benign and malignant pleural disease

Monaldi Archives for Chest Disease, 2005
Background. CT plays a valuable role in assessment of patients with a wide variety of diseases of the pleura, and pulmonologists should be aware of the significance of different CT findings for the differential diagnosis of benign and malignant pleural ...
U. Yilmaz, G. Polat, N. Sahin, Ö. Soy, U. Gülay   +4 more
doaj   +1 more source