Results 61 to 70 of about 175,117 (320)

A 3D Biofabricated Disease Model Mimicking the Brain Extracellular Matrix Suitable to Characterize Intrinsic Neuronal Network Alterations in the Presence of a Breast Tumor Disseminated to the Brain

Advanced Functional Materials, EarlyView.
A 3D disease model is developed using customized hyaluronic‐acid‐based hydrogels supplemented with extracellular matrix (ECM) proteins resembling brain ECM properties. Neurons, astrocytes, and tumor cells are used to mimic the native brain surrounding.
Esra Türker, Mateo S. Andrade Mier, Jessica Faber, Mike Friedrich, Zan Lamberger, Jeannette Weigelt, Christian Stigloher, Nicoletta Murenu, Natascha Schaefer, Jörg Tessmar, Gregor Lang, Silvia Budday, Katrin G. Heinze, Antje Appelt‐Menzel, Pamela L. Strissel, Reiner Strick, Carmen Villmann   +16 more
wiley   +1 more source

Added value of diffusion-weighted MRI in assessment of pleural lesions

The Egyptian Journal of Radiology and Nuclear Medicine, 2021
Background There are many causes of pleural disease including variable benign and malignant etiologies. DWI is a non-enhanced functional MRI technique that allows qualitative and quantitative characterization of tissues based on their water molecules ...
Youssriah Yahia Sabri, Ikram Hamed Mahmoud, Lamis Tarek El-Gendy, Mohamed Raafat Abd El-Mageed, Sally Fouad Tadros   +4 more
doaj   +1 more source

Estimating past inhalation exposure to asbestos: a tool for risk attribution and disease screening [PDF]

, 2017
Introduction: Late presentation is common in mesothelioma. Reliable assessment of past exposure to asbestos is a necessary first step for risk attribution and for the development of a future screening programme. Such a programme could maximise access
Blyth, Kevin G., Cherrie, John W., McElvenny, Damien   +2 more
core   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

ALDOA‐Mediated Metabolic Reprogramming is a Targetable Vulnerability for Ferroptosis Sensitization in Cancer

Advanced Science, EarlyView.
ALDOA‐depletion‐mediated glycolytic reprogramming promotes autophagy‐mediated degradation of MBOAT2, increasing the ratio of phospholipids containing pro‐ferroptotic polyunsaturated fatty acids over anti‐ferroptotic monounsaturated fatty acids, and thus sensitizing cancer cells to ferroptosis.
Pengqi Wang, Kezhang He, Bowen Wang, Wei Zhou, Ying Zhang, Tianhua Ma, Sheng Ding   +6 more
wiley   +1 more source

A RARE CASE OF PERICARDIAL AND PLEURAL EFFUSION IN GRAVES' DISEASE [PDF]

, 2023
SAIF AL-DEEN ALATTAL, Sara AlAttal, HARITH GHNAIMA, SURYA CHENNUPATI, DINA SHABAN, GEORGETTE NADER, RAJIT PAHWA   +6 more
openalex   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Medical thoracoscopy versus image-guided pleural biopsy for diagnosing pleural diseases

Egyptian Journal of Chest Disease and Tuberculosis, 2018
Background The diagnostic role of medical thoracoscopy and image-guided pleural biopsy in patients with undiagnosed exudative pleural effusion has increased over the last few years.
Emad Ibrahim, Rasha Daabis, Alaa Abdallah, Amr Abdelkerim, Mervat A Ismail   +4 more
doaj   +1 more source

Pleural effusion in sarcoidosis patients

Туберкулез и болезни лёгких, 2020
The article presents the review of 62 publications which demonstrated that 1.1-16.7% of patients with pulmonary sarcoidosis develop plural effusion.
N. A. Stogova
doaj   +1 more source

P103 Provision of pleural disease care in the pandemic era: A single centre experience [PDF]

, 2021
Khalil Ur Rehman, Jianhong Liang, Parthipan Sivakumar   +2 more
openalex   +1 more source