Results 131 to 140 of about 45,501 (263)

Metastatic Squamous Cell Carcinoma Treated With Pembrolizumab in a Patient With Xeroderma Pigmentosum

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT A 5‐year‐old male with xeroderma pigmentosum from Honduras presented with a rapidly growing mass on the left post‐auricular neck, associated with left‐sided hearing loss. MRI revealed a large mass with invasion of the external auditory canal, temporal bone, and metastasis to lymph nodes. Biopsy confirmed moderately differentiated squamous cell
Ngan Do   +4 more
wiley   +1 more source

A prospective non‐inferiority trial of pathogen reduced platelets compared to non‐pathogen reduced platelets for correction of viscoelastic platelet function testing in cardiac surgery

open access: yesTransfusion, EarlyView.
Abstract Background Cardiac surgery on cardiopulmonary bypass (CPB) may alter platelet (PLT) function causing bleeding. The goal of this study is to evaluate the hemostatic effect of PRT‐PLTs compared to untreated PLTs stored in platelet additive solution (PAS) following transfusion in bleeding patients undergoing cardiac surgery on CPB.
Magali J. Fontaine   +11 more
wiley   +1 more source

Retrospective Study Evaluating Outcomes Following Palliative Radiotherapy With or Without Chemotherapy for Dogs With Presumed Cardiac Hemangiosarcoma

open access: yesVeterinary and Comparative Oncology, EarlyView.
ABSTRACT Canine cardiac hemangiosarcoma (cHSA) represents a complex clinical challenge in that those afflicted have an acute risk of death due to cardiac tamponade and high morbidity and mortality given the frequency of metastasis. Previous studies show that radiation therapy (RT) can decrease the risk of tamponade; however, an optimal approach has yet
Cory N. Wakamatsu   +4 more
wiley   +1 more source

Transforming treatment paradigms: Focus on personalized medicine for high‐grade serous ovarian cancer

open access: yesCA: A Cancer Journal for Clinicians, EarlyView.
Abstract High‐grade serous ovarian cancer (HGSOC) is the most common and aggressive subtype of ovarian cancer, accounting for approximately 70% of all ovarian cancer cases and contributing significantly to the high mortality rates associated with this disease.
Pawel Kordowitzki   +6 more
wiley   +1 more source

A simplified technique for the treatment of simple pleural effusions [PDF]

open access: yes, 1987
This technique for the drainage of simple pleural effusions is simple, safe and effective. It requires little more skill than the ability to perform a thoracentesis or central venous line placement.
Shaw, BW   +3 more
core  

Case Report: Hematopoietic Stem Cell Transplantation to Treat Severe Acquired Aplastic Anemia in a Pediatric Kidney Transplant Recipient

open access: yesPediatric Transplantation, Volume 29, Issue 5, August 2025.
ABSTRACT Background Hematopoietic stem cell transplantation (HSCT) in solid organ transplant recipients has been reported in adults. However, data on children are scarce. We report a case of an allogeneic HSCT in a 14‐year‐old girl to treat idiopathic very severe aplastic anemia (SAA). Case Presentation The girl developed end‐stage renal disease at the
Gintarė Mierkienė   +4 more
wiley   +1 more source

What Is the Expected Clearance of Methotrexate? A Therapeutic Drug Monitoring Reference Guide for High‐Dose Methotrexate Use in Pediatric Malignancies

open access: yesPediatric Blood &Cancer, Volume 72, Issue 7, July 2025.
ABSTRACT High‐dose methotrexate dosage and infusion durations differ across treatment protocols for pediatric leukemia, lymphoma, and osteosarcoma. Supportive care interventions are dependent on a patient's elimination of methotrexate (MTX). Therefore, it is important to establish the expected MTX elimination across protocols.
Zachary L. Taylor   +11 more
wiley   +1 more source

Guideline for the Management Pathway and Quality Control of Breast Cancer Prevention and Treatment in China's Counties

open access: yesCancer Innovation, Volume 4, Issue 3, June 2025.
County hospitals bear the primary responsibility for health education, screening, primary diagnosis and treatment, maintenance treatment, management of adverse reactions to antitumor drugs, patient follow‐up, recurrence monitoring, rehabilitation guidance, and two‐way referrals for breast cancer.
Breast Cancer Expert Committee of National Cancer Quality Control Center   +1 more
wiley   +1 more source

Diagnostic value of Neuron-Specific Enolase (NSE) and Cancer Antigen 15-3 (CA 15-3) in the Diagnosis of Pleural effusions [PDF]

open access: yes, 2017
Introduction: Pleural effusion diagnosis plays an important role in determining treatment strategies. The aim of this study was to determine the diagnostic capacity of tumor markers CA 15-3 and NSE solely or in combination in differentiating the nature ...
Ehteram, H.   +4 more
core  

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