Results 111 to 120 of about 58,831 (274)

An update on the landscape of collagen bioactive fragments

open access: yesThe FEBS Journal, EarlyView.
The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley   +1 more source

Malignant melanoma presenting as an isolated pleural effusion

open access: yes, 2015
Isolated pleural effusion is a very rare presentation of malignant melanoma. A 46 year-old male patient presented to us with complaints of shortness of breath during the previous month.
Z. Ahmed   +7 more
core   +1 more source

Management of Breakthrough Bleeding During Emicizumab Prophylaxis in Acquired Haemophilia A: Data From the GTH‐AHA‐EMI Study

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction The GTH‐AHA‐EMI study showed that emicizumab reduces bleeding in patients with acquired haemophilia A (AHA). However, 22 clinically relevant new bleeds (CRNB) occurred in 14 of the 47 study patients, most of which required haemostatic treatment.
Halet Türkantoz   +11 more
wiley   +1 more source

Implantation of permanent pleural catheter for palliation of malignant pleural effusion

open access: yes, 2016
Michelle Meier,1 Marie Riis Mortensen,1 Lene Unmack Larsen2 1Department of Surgical Gastroenterology, 2Department of Radiology, Aarhus University Hospital, Aarhus, Denmark Purpose: Malignant pleural effusion (MPE) is a disabling condition caused in most ...
Larsen LU, Mortensen MR, Meier M
core  

The utility of survivin mRNA as a diagnostic biomarker in lung cancer with malignant pleural effusion

open access: yesEgyptian Journal of Chest Disease and Tuberculosis, 2012
Introduction: The sensitivity of conventional cytology for the detection of malignant cells in pleural effusion is insufficient. Since survivin is frequently overexpressed in lung cancer, it might play a role in oncogenesis and progression of the tumor ...
Gehan H. Abo El-Magd   +3 more
doaj   +1 more source

The 2025 ATS/ERS update of the international multidisciplinary classification of the interstitial pneumonias: implications for the pathologist

open access: yesHistopathology, EarlyView.
This review highlights changes relevant to pathologists in the updated multidisciplinary classification of interstitial pneumonias. Changes include expansion beyond idiopathic disease, subclassification as interstitial (fibrotic vs non‐fibrotic) and alveolar filling disorders, expansion to include additional patterns (e.g.
Andrew G Nicholson   +7 more
wiley   +1 more source

Australian clinical practice guideline: diagnosis and treatment of idiopathic multicentric Castleman disease

open access: yesInternal Medicine Journal, EarlyView.
Abstract Idiopathic multicentric Castleman disease (iMCD) is a rare condition. The pathogenesis is incompletely understood; however, interleukin‐6 (IL‐6) is a major mediator. The clinical presentation is heterogeneous, from mild constitutional symptoms to severe multi‐organ failure.
Dipti Talaulikar   +16 more
wiley   +1 more source

Management of malignant pleural effusion: Options and recommended approaches

open access: yes, 2013
There is no consensus on the best management of symptomatic malignant pleural effusion. Drainage with a small bore pleural catheter is preferred over a wide bore catheter or recurrent pleural aspiration in patients with symptomatic malignant pleural ...
Leung, L, Lam, KC, Hsin, M
core   +1 more source

Predictive Ability of Sonographic Characteristics Alone to Diagnose Tuberculous Pleural Effusions in a Resource‐Limited Setting: A Cross‐Sectional Pilot Study in Zambia

open access: yesTropical Medicine &International Health, EarlyView.
ABSTRACT Background Tuberculous pleural effusion (TPE), the second most common form of extra‐pulmonary tuberculosis (TB), remains difficult to diagnose due to low‐yield, invasive and often unavailable diagnostics in resource‐limited settings. This study aimed to evaluate the diagnostic accuracy of sonographic characteristics alone to predict TB ...
Lukonde Zimba   +3 more
wiley   +1 more source

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