Results 91 to 100 of about 153,974 (300)

Clinical trial of safety and antitumor activity of farletuzumab ecteribulin in patients with platinum‐resistant ovarian cancer: Phase I expansion results

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective In the dose‐escalation part of Study 101, which included multiple tumor types, objective responses were observed in 10 of 22 patients across multiple dose levels of farletuzumab ecteribulin (FZEC). We explored the safety/antitumor activity of FZEC in patients with platinum‐resistant ovarian cancer (PROC) from the Study 101 expansion ...
Kan Yonemori, Mayu Yunokawa, Koji Matsumoto, Kazuhiro Takehara, Kosei Hasegawa, Yasuyuki Hirashima, Hidenori Kato, Hiroki Ikezawa, Yohei Otake, Wataru Yusa, Takuma Miura, Shin Nishio   +11 more
wiley   +1 more source

Diagnostic value of cyfra 21-1 and carcinoembryonic antigen in differentiation between benign and malignant pleural effusion

Egyptian Journal of Chest Disease and Tuberculosis, 2015
Background: Tumor markers were used in malignant pleural effusion with negative cytology. Aim of the work: The aim was to assess the value of serum and pleural levels of cyfra 21-1 (fragment of cytokeratin 19) and carcinoembryonic antigen (CEA) in the ...
Waffa S. El-Shimy, Basem I. El-Shafey, Hesham A. El-Sorougy, Eman Ali Abd El-Monem   +3 more
doaj   +1 more source

Diagnostic value of medical thoracoscopy in malignant pleural effusion

BMC Pulmonary Medicine, 2017
BackgroundMedical thoracoscopy has been shown to be an efficacious procedure in diagnosing unexplained exudative pleural effusions with excellent safety. This study aimed to assess the diagnostic significance of thoracoscopy in the management of patients
Yan-bing Wu, Li-li Xu, Xiao-juan Wang, Zhen Wang, Jun Zhang, Z. Tong, Huanzhong Shi   +6 more
semanticscholar   +1 more source

Postoperative Weight Gain, Due to Fluid Retention After Ovarian Cancer Surgery—How Much Is too Much?

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives Postoperative complications after cytoreductive surgery in ovarian cancer patients are associated with impaired survival. Here, we investigated the association between postoperative weight gain due to fluid retention and the development of complications and anastomotic leakage (AL).
Eva K. Egger, Melisa Delen, Hanno Matthaei, Laura Tascon Padron, Carolin Schröder, Milka Marinova, Dominique Koensgen, Alexander Mustea   +7 more
wiley   +1 more source

Matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in diagnosis of pleural effusion of malignant origin [PDF]

, 2016
OBJECTIVES: The aim of the present study was to evaluate the diagnostic accuracy of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in differentiating benign from malignant exudative pleural effusions.
D'Angelo, L., Di Carlo, A., Di Domenico, M., Feola, A., Fiorelli, A., Mazzella, A., Ricci, S., Santini, M.   +7 more
core   +1 more source

Leptin In Malign Pleural Efusions: May Be A New Marker?

Ankara Üniversitesi Tıp Fakültesi Mecmuası, 2011
Objective: The pleural effusions may be caused by malignant or benign diseases. In this study, it was aimed to determine the serum and pleural leptin levels in non-malignant and malignant pleural effusions.Methods: Patients with non-malignant (n=20) and ...
Serap Duru, Zeynep Sönmez, Yasemin Saygıdeger, Alper Dilli, Günnur Dikmen, Özlem Sever, Sadık Ardıç   +6 more
doaj   +1 more source

Predicting survival in malignant pleural effusion: development and validation of the LENT prognostic score [PDF]

, 2014
BACKGROUND: Malignant pleural effusion (MPE) causes debilitating breathlessness and predicting survival is challenging. This study aimed to obtain contemporary data on survival by underlying tumour type in patients with MPE, identify prognostic ...
Amelia O Clive, Andrew R L Medford, Anevlavis, Anna J Morley, Bielsa, Brennan C Kahan, Burrows, Claire L Tobin, Clare E Hooper, Curran, Davies, Dresler, Edward T H Fysh, Harrell, Heffner, Herndon, John E Harvey, Kahan, Kao, Li, Martinez-Moragon, Michel M van den Heuvel, Natalie Zahan-Evans, Nick A Maskell, Oliver J Bintcliffe, Ozyurtkan, Pilling, Pinato, Proctor, Putnam, Rahul Bhatnagar, Roberts, Rogier C Boshuizen, Royston, Suzuki, Tan, White, Y C Gary Lee   +37 more
core   +3 more sources

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Cost‐effectiveness of indwelling pleural catheter compared with talc in malignant pleural effusion

Respirology (Carlton South. Print), 2017
Malignant pleural effusion is associated with morbidity and mortality. A randomized controlled trial previously compared clinical outcomes and resource use with indwelling pleural catheter (IPC) and talc pleurodesis in this population.
Jordan A P Olfert, E. Penz, B. Manns, Eleanor K. Mishra, H. Davies, Robert F Miller, R. Luengo-Fernandez, Song Gao, N. Rahman   +8 more
semanticscholar   +1 more source

Diagnostic accuracy of tumor necrosis factor-alpha, interferon-gamma, interlukine-10 and adenosine deaminase 2 in differential diagnosis between tuberculous pleural effusion and malignant pleural effusion [PDF]

, 2014
BACKGROUND: The current study was performed to investigate the potential biomarkers for the differential diagnosis of tuberculous pleural effusion (TPE) and malignant pleural effusions (MPE). METHODS: Among ninety patients (n = 90) involved in the study,
Helin Wang, Jian Huang, Junxiang Wang, Mingying Li, Xia Wang, Xiue Xi   +5 more
core   +1 more source