Results 241 to 250 of about 153,974 (300)
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Malignant Pleural Effusion: Presentation, Diagnosis, and Management.

American Journal of Medicine, 2022
Malignant pleural effusions are common in patients with cancer. Most malignant pleural effusions are secondary to metastases to the pleura, most often from lung or breast cancer.
S. Gayen
semanticscholar   +1 more source

Malignant Pleural Effusions

Clinics in Chest Medicine, 2021
Malignant pleural effusions have a significant burden on patients and the health care system. Diagnosis is typically via thoracentesis, although other times more invasive procedures are required. Management centers around relief of dyspnea and patient quality of life and can be done via serial thoracentesis, indwelling pleural catheter, or pleurodesis.
Christopher M, Kapp, Hans J, Lee
openaire   +2 more sources

Translational Nanotherapeutics Reprograms Immune Microenvironment in Malignant Pleural Effusion of Lung Adenocarcinoma

Advanced Healthcare Materials, 2021
Malignant pleural effusion (MPE) remains a treatment bottleneck in advanced lung cancer, due to its complicated microenvironments and “cold” immunity. Therefore, the search for therapeutic drugs to transform MPE to functionally “hot” one could advance ...
Zhenhuan Song   +5 more
semanticscholar   +1 more source

Malignant Pleural Effusions

Seminars in Respiratory and Critical Care Medicine, 1985
Various diseases of the gastrointestinal tract at times are accompanied by an exudative pleural effusion. The exudative pleural effusions resulting from esophageal perforation, pancreatic disease, subphrenic abscess, intrahepatic abscess, splenic abscess, abdominal operations, and diaphragmatic hernia are discussed in this article.
B H, Gobel, P E, Lawler
openaire   +5 more sources

Malignant pleural effusions

Cancer Treatment Reviews, 1978
Recurrent malignant pleural effusion is a relatively common problem that often occurs many months before the terminal stages of a patient's malignant disease. Despite careful evaluation, it is often impossible to identify the exact physiologic cause of an effusion and difficult to identify a pragmatic course of therapy.
M A, Friedman, E, Slater
openaire   +2 more sources

Macrophage-derived CCL22 promotes an immunosuppressive tumor microenvironment via IL-8 in malignant pleural effusion.

Cancer Letters, 2019
Immune dysfunction often occurs in malignant pleural effusion (MPE). In our previous study, TGF-β derived predominantly from macrophages plays an important role in impairing T cell cytotoxicity in MPE.
Dong Wang   +10 more
semanticscholar   +1 more source

Autologous tumor cell–derived microparticle-based targeted chemotherapy in lung cancer patients with malignant pleural effusion

Science Translational Medicine, 2019
This study investigated the application of a therapeutic tumor cell–derived microparticle-based nanodelivery platform in malignant pleural effusion. Insider attack on tumors A major factor that limits the effectiveness of cancer therapy is the ability to
Mengfei Guo   +21 more
semanticscholar   +1 more source

Phenotyping malignant pleural effusions

Current Opinion in Pulmonary Medicine, 2016
Patients with malignant pleural effusions (MPEs) are heterogenous in their disease course, symptom severity, responses to cancer therapies, fluid recurrence rates, and thus need for definitive fluid control measures. To tailor the most appropriate treatment for individual patients, clinicians need to 'phenotype' the patients and predict their clinical ...
Macy M S, Lui   +2 more
openaire   +2 more sources

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