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Management of Malignant Pleural Effusions

Chest, 1993
Malignant pleural effusions (MPEs) are a common complication of advanced malignancies, particularly lung and breast cancer. They are caused by a variety of mechanisms including tumor obstruction of lymphatic flow, spread of malignant cells via the systemic circulation, and tumor invasion of the pulmonary arterioles.
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Treatment of Malignant Pleural Effusion

Chest, 1985
Two hundred consecutive patients with malignant pleural effusion were reviewed. The pathologic etiology of malignant pleurisy was: primary lung cancer in 123 cases; five, mesothelioma; and 72 cases secondary to metastatic tumors. Adenocarcinoma of the lung and mammary cancer were the most frequent tumors causing malignant pleural effusion.
K, Reshad   +4 more
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Treatment of malignant pleural effusions

Current Opinion in Pulmonary Medicine, 1999
Malignant pleural effusions are common in cancer patients with advanced disease. These patients usually present with chest pain, cough, and progressive shortness of breath, all of which may cause significant impairment in quality of life. Therapeutic options include systemic treatment; thoracentesis; or, most commonly, tube drainage and sclerotherapy ...
J J, Erasmus, E F, Patz
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Eosinophils, Pleural Effusions, and Malignancy

Annals of Internal Medicine, 1978
Excerpt To the editor: The concise review of malignant pleural effusion by Leff, Hopewell, and Costello (1) was a delight to read.
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Management of malignant pleural effusions

Current Opinion in Pulmonary Medicine, 2011
Malignant pleural effusions (MPEs) are one of the most common problems faced by clinicians and, since there is no optimum treatment available, they deserve efforts aimed to improve their management.We have reviewed the most recent articles regarding treatment of MPE, with special emphasis on pleurodesis and indwelling pleural catheter placement ...
Rodríguez-Panadero, F.   +1 more
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Phenotyping malignant pleural effusions

Current Opinion in Pulmonary Medicine, 2016
Patients with malignant pleural effusions (MPEs) are heterogenous in their disease course, symptom severity, responses to cancer therapies, fluid recurrence rates, and thus need for definitive fluid control measures. To tailor the most appropriate treatment for individual patients, clinicians need to 'phenotype' the patients and predict their clinical ...
Macy M S, Lui   +2 more
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MANAGEMENT OF THE MALIGNANT PLEURAL EFFUSION

Chest Surgery Clinics of North America, 1994
The proper management of a pleural effusion in a patient with malignancy is based on an understanding of the normal anatomy and physiology of the pleural space and the ways in which they are altered by disease. The major challenge in diagnosing and treating a cancer patient who develops a pleural effusion is determining the cause of the effusion ...
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Management of Malignant Pleural Effusions

Seminars in Respiratory and Critical Care Medicine, 2008
Malignant pleural effusions (MPEs) are commonly seen as complications of advanced malignancy, especially in lung cancer and breast cancer. The management will depend on the performance status of the patient, severity of the symptoms, and the primary tumor's response to systemic therapy.
Marcelo, Spector, Jeffrey S, Pollak
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Treatment of Malignant Pleural Effusions

Clinics in Chest Medicine
This review addresses the treatment options for malignant pleural effusions by evaluating the multiple possible pathways to achieving fluid control. High pleurodesis rates can be achieved either by talc slurry with a chest drain, or talc poudrage via thoracoscopy. Outpatient management, using indwelling pleural catheters (IPCs), enables ambulatory home-
Rebecca, Crook   +2 more
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Pleurodesis for malignant pleural effusions

Cochrane Database of Systematic Reviews, 2000
Approximately half of all patients with metastatic cancer develop a malignant pleural effusion which is likely to lead to a significant reduction in quality of life secondary to symptoms such as dyspnoea and cough. The aim of pleurodesis in these patients is to prevent re-accumulation of the effusion and thereby of symptoms, and avoid the need for ...
P, Shaw, R, Agarwal
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