Results 161 to 170 of about 124,217 (217)

Stage IV Ovarian Cancer Is Not Uniformly Lethal: Two Subgroups With Stage II‐Like Outcomes Identified in Large Retrospective Cohorts

open access: yesCancer Medicine, Volume 15, Issue 11, November 2026.
ABSTRACT Background The International Federation of Gynecology and Obstetrics (FIGO) staging system for advanced ovarian cancer has remained largely static since 2014, with stage IV subdivided into IVA and IVB without further stratification. Emerging evidence suggests substantial prognostic heterogeneity within stage IV, yet large‐scale validation ...
Cheng Fang, Jundong Li, Qiaqia Li
wiley   +1 more source

Massive Pericardial Effusion as a Manifestation of Severe Autoimmune Hypothyroidism in an Adolescent With Down Syndrome: Importance of Early Recognition and Thyroid Hormone Replacement

open access: yesClinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT The clinical features of severe hypothyroidism may overlap with those of Down syndrome, delaying diagnosis until complications such as myxedema crisis and massive pericardial effusion develop. Regular thyroid function screening is essential, and hypothyroidism‐associated massive pericardial effusion can often be treated conservatively with ...
Bivek Mishra   +6 more
wiley   +1 more source

Preanalytical variables affect predictive immunohistochemical biomarker testing in non–small cell lung carcinoma cytology specimens

open access: yesCancer Cytopathology, Volume 134, Issue 11, November 2026.
Abstract Background Several therapeutic targets for non–small cell lung carcinoma (NSCLC) rely on protein expression by immunohistochemistry (IHC). Most biomarkers are validated on formalin‐fixed, paraffin‐embedded (FFPE) tissue; however, cytologic specimens, including cell blocks (CBs), that are subject to preanalytical variables are increasingly used.
Saroja Devi Geetha   +3 more
wiley   +1 more source

Surgical Removal of Residual Tumor Masses in Patients Undergoing Targeted Therapy for EGFR‐Mutated Locally Advanced or Metastatic Lung Cancer

open access: yesInternational Journal of Cancer, Volume 159, Issue 9, Page 2244-2261, 1 November 2026.
Non‐small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations often exhibit significant tumor reduction following tyrosine kinase inhibitor (TKI) therapy. Residual tumors frequently remain, however, leading to drug resistance and disease progression.
Fedor Moiseenko   +31 more
wiley   +1 more source

Liquid Biopsy: Past, Present, and Future

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Liquid biopsy has expanded from cancer genotyping to a broader strategy for probing both oncologic and nononcologic conditions through circulating analytes and multilayer molecular readouts. This review traces the field's past, present, and future—summarizing where liquid biopsy is most actionable today, why performance varies across contexts, and ...
Jiachen Liu   +8 more
wiley   +1 more source

Left Medial Liver Lobe Torsion Associated With Hepatocellular Carcinoma in a Pembroke Welsh Corgi: A Case Report

open access: yesVeterinary Medicine and Science, Volume 12, Issue 6, November 2026.
In a 12‐year‐old Pembroke Welsh Corgi, hepatocellular carcinoma was associated with left medial liver lobe torsion, with the torsion axis located at the base of the mass rather than at the hepatic hilus. Computed tomography revealed a whirl sign at this atypical site, enabling preoperative diagnosis and surgical planning.
Hitomi Shinoda   +4 more
wiley   +1 more source

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