Results 61 to 70 of about 314,927 (315)

Intractable pleural effusion associated with superior vena cava and upper extremity deep vein thrombosis in a patient with advanced lung cancer

Respiratory Medicine Case Reports, 2020
We herein report a case with intractable pleural effusion attributed to superior vena cava (SVC) and upper extremity deep vein thrombosis in a patient with lung cancer.
Kosuke Tsuruno, Kazunori Tobino, Mitsukuni Sakabe, Masanobu Okahisa, Saori Nishizawa, Kohei Yoshimine, Yuki Ko, Hiromi Ide   +7 more
doaj   +1 more source

Targeting PRKCN, an Essential Driver Orchestrating mTOR‐IRF4 Axis Independently of Kinase Activity, in Multiple Myeloma

Advanced Science, EarlyView.
Constitutive PRKCN expression is driven by super‐enhancers and modulated by NF‐κB signaling in multiple myeloma (MM). PRKCN activates mTORC1/2‐IRF4 signaling axis and favors tumor cell growth independently of its kinase activity. IRF4 reciprocally promotes PRKCN transcription, creating a feed‐forward loop.
Koukou Tang, Dongpeng Jiang, Peng Ke, Xiaosen Bian, Lili Zhang, Ying Zhang, Tingting Zhu, Weiwei Qu, Wenhui Qi, Yang Xu, Chengcheng Fu, Depei Wu, Jianhong Chu   +12 more
wiley   +1 more source

Pleural Effusion Identified by Point of Care Ultrasound (POCUS) in Septic Shock: Impact on Clinical Outcomes

POCUS Journal
Aim: To analyze the association between pleural effusion detected by chest point of care ultrasound (POCUS) and clinical outcomes in patients with septic shock admitted to an intensive care unit (ICU).
Erick Joel Rendón-Ramirez, Andrés Mauricio Morales-García, Adrián Rendón-Pérez, Homero Nañez-Terreros, Ricardo César Solis, Alexandra Daniela Magaña-García, Samantha Medrano-Juárez, José Francisco Caloca-Estrada, Roberto Mercado-Longoria, Jorge Eduardo Leija-Herrera, José M Porcel   +10 more
doaj   +1 more source

Malignant pleural mesothelioma with resolution of pleural effusion

Respirology Case Reports, 2023
Key message In malignant pleural mesothelioma patients, pleural effusion may improve during the course of the disease. Pleural effusion with nodular shadows bordering the pleura should be followed up even if the pleural effusion improves.
Sayaka Nishida, Kazutoshi Toriyama, Makiko Yomota, Yukio Hosomi   +3 more
doaj   +1 more source

Integrative Approaches to Treating Cellular Senescence in Kidney Disease

Advanced Science, EarlyView.
ABSTRACT Cellular senescence in the kidney plays a crucial role in the progression of acute kidney injury and chronic kidney disease. Therapeutic approaches targeting senescent cells, such as small molecule senolytic and senomorphic drugs, display efficacy in preclinical models.
Tomoka Misawa, Amruta A, LaTonya J. Hickson, Joy Wolfram   +3 more
wiley   +1 more source

Peroxidase‐Mimicking Nanozymes for Rapid Detection of Infectious Diseases

Advanced Science, EarlyView.
Peroxidase‐mimicking nanozymes (PMNs) have emerged as robust and versatile materials for rapid infectious disease diagnostics. This review highlights the rational design and controlled synthesis of PMNs, summarizes key biomarkers relevant to infectious diseases, examines their integration into diverse rapid detection platforms, and highlights ...
Shikuan Shao, Victor Fernandez‐Gonzalez, Xiaochuan Wang, Blake Pylipow, Claudia Herrera, Xiaohu Xia   +5 more
wiley   +1 more source

Diagnostic value of medical thoracoscopy in malignant pleural effusion

BMC Pulmonary Medicine, 2017
BackgroundMedical thoracoscopy has been shown to be an efficacious procedure in diagnosing unexplained exudative pleural effusions with excellent safety. This study aimed to assess the diagnostic significance of thoracoscopy in the management of patients
Yan-bing Wu, Li-li Xu, Xiao-juan Wang, Zhen Wang, Jun Zhang, Z. Tong, Huanzhong Shi   +6 more
semanticscholar   +1 more source

Pyroptosis‐Inducing Engineered Microparticles for Cancer Immunotherapy

Advanced Science, EarlyView.
Engineered microparticles co‐delivering geldanamycin and dual nanobodies induce targeted pyroptosis and block PD‐L1 and CD47 pathways, reprogramming the tumor microenvironment and achieving potent antitumor immunity in lung cancer models with minimal toxicity.
Tianli Hao, Zihan Deng, Yufei Liu, Li Liu, Deqiang Deng, Muyang Yang, Yuanyuan Geng, Yao Sun, Beilei Yue, Jonathan F. Lovell, Yushuai Liu, Lisen Lu, Honglin Jin   +12 more
wiley   +1 more source

Assessment of the histopathological prototypes of the pleural fluid and granulomatous tissue reaction associated with pleural tuberculosis

Egyptian Journal of Chest Disease and Tuberculosis, 2014
Purpose: The aim of this study is to differentiate between the histopathological features of pleural tuberculosis both free and encysted forms of pleural effusion as regards pleural fluid cytology and pleural tissue granulomatous tissue reaction and ...
A.M. Abumossalam, A.A. Moawd, A.M. Shebl
doaj   +1 more source

Characteristic pattern of pleural effusion in electrical impedance tomography images of critically ill patients

British Journal of Anaesthesia, 2018
Background: Electrical impedance tomography (EIT) is increasingly used for continuous monitoring of ventilation in intensive care patients. Clinical observations in patients with pleural effusion show an increase in out‐of‐phase impedance changes.
T. Becher, M. Bussmeyer, I. Lautenschläger, D. Schädler, N. Weiler, I. Frerichs   +5 more
semanticscholar   +1 more source