Results 101 to 110 of about 7,465 (255)
Increased nuclear translation of YAP might act as a potential therapeutic target for NF1-related plexiform neurofibroma [PDF]
, 2021 Jialiang Liu +6 more
openalex +1 more source
Trametinib in Adults with Neurofibromatosis Type 1‐Related Symptomatic Plexiform Neurofibromas
Annals of Neurology, Volume 99, Issue 1, Page 73-83, January 2026.Objective Mitogen‐activated protein kinase kinase inhibitors have shown promising results in treatment of plexiform neurofibromas in neurofibromatosis type 1 patients, but data in adults are limited. The aim of this phase 2 study was to investigate the efficacy and safety of trametinib in adults with neurofibromatosis type 1.
D. Christine Noordhoek +7 more
wiley +1 more source
Síndrome de moyamoya associada a neurofibromatose tipo I em paciente pediátrico [PDF]
, 2011 CONTEXT: Neurofibromatosis type 1 (NF-1) is the most prevalent autosomal dominant genetic disorder among humans. Moyamoya disease is a cerebral vasculopathy that is only rarely observed in association with NF-1, particularly in the pediatric age range ...
DARRIGO JÚNIOR, Luiz Guilherme +5 more
core +1 more source
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 1, January 2026.ABSTRACT A twice‐daily administration of oral selumetinib (SLT) in the fasted state is the only approved pharmaceutical option for treating inoperable neurofibromatosis type I (NF‐1) and plexiform neurofibromas (PN). In children, exposure to SLT is highly variable, and fasting presents a substantial burden.
Zoltán Köllő +7 more
wiley +1 more source
Clinically aggressive central giant cell granulomas in two patients with neurofibromatosis 1 [PDF]
, 2006 Background Neurofibromatosis 1 (NF1) is an autosomal dominantly inherited disorder caused by a spectrum of mutations affecting the Nf1 gene. Affected patients develop benign and malignant tumors at an increased frequency.
Edwards, Paul C. +5 more
core +1 more source
Journal of Oral Pathology &Medicine, Volume 55, Issue 1, Page 155-160, January 2026.ABSTRACT Objective The aim of this study was to determine the prevalence of oral alterations detectable through physical examination in NF1 individuals. Additionally, we assessed the correlation between the number of oral and cutaneous neurofibromas. Design This retrospective study evaluated oral alterations in individuals with and without NF1.
Pâmella de Pinho Montovani +3 more
wiley +1 more source
Acute median nerve palsy due to hemorrhaged schwannoma: case report [PDF]
, 2007 Schwannomas are common, benign nerve tumors originating from the sheath of peripheral nerves. In this article, a 54 year old woman suffered from sudden onset motor and sensory deficit at her first radial three fingers on her right hand.
Mehmet Aydin +2 more
core +2 more sources
Malignant peripheral nerve sheath tumour: A rare tumour of the breast [PDF]
, 2010 Malignant peripheral nerve sheath tumour is a rare tumour of the breast and this report highlights the radiological and histological features and the difficulties in making a diagnosis. A high index of suspicion when dealing with a breast lesion that has
Akhator, A +3 more
core
Cervical and Spinal Plexiform Neurofibroma: A Case Report
, 2021 El Azzouzi B +4 more
openalex +1 more source
Plexiform Neurofibroma of the Submandibular Salivary Gland in a Child
Canadian Journal of Gastroenterology, 2001 Plexiform neurofibromas in major salivary glands are rarely described. In the literature, most reported tumours have been present in the parotid gland region.
Jacqueline M Bourgeois +3 more
doaj +1 more source