Results 151 to 160 of about 29,620 (204)
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Management of Plexiform Neurofibroma of the Larynx
Annals of Otology, Rhinology and Laryngology, 1987We report the ninth case of plexiform neurofibroma of the larynx, which occurred in a 2-year-old with multiple café au lait spots and obstructive sleep apnea. In discussing this clinical problem, we have attempted to make the following points. 1) A patient's having more than six café au lait spots of greater than 1.5-cm diameter is diagnostic of von ...
Robert E Wood
exaly +3 more sources
International Journal of Oral & Maxillofacial Surgery, 2023
Neurofibromas are frequently present in the skin, but are uncommon in the oral and maxillofacial region. There are three histological variants of neurofibroma: localized, diffuse, and plexiform.
Y. Zhang, M. Chen, F. Petersson, A. Lim
semanticscholar +1 more source
Neurofibromas are frequently present in the skin, but are uncommon in the oral and maxillofacial region. There are three histological variants of neurofibroma: localized, diffuse, and plexiform.
Y. Zhang, M. Chen, F. Petersson, A. Lim
semanticscholar +1 more source
FDA Approval Summary: Selumetinib for Plexiform Neurofibroma
Clinical Cancer Research, 2021On April 10, 2020, the FDA approved selumetinib (KOSELUGO, AstraZeneca) for the treatment of pediatric patients 2 years of age and older with neurofibromatosis type 1 who have symptomatic, inoperable plexiform neurofibromas.
Denise Casey +27 more
semanticscholar +1 more source
Current Medical Research and Opinion, 2021
Plexiform neurofibroma (PN) is one of the most striking clinical features of neurofibromatosis 1. Growth of PN can occur at any stage of life but mostly in childhood and during hormonal changes.
S. Mukhopadhyay +2 more
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Plexiform neurofibroma (PN) is one of the most striking clinical features of neurofibromatosis 1. Growth of PN can occur at any stage of life but mostly in childhood and during hormonal changes.
S. Mukhopadhyay +2 more
semanticscholar +1 more source
The Laryngoscope, 1977
AbstractFacial plexiform neurofibroma is a relatively rare manifestation of Von Recklinghausen's neurofibromatosis. Two patients with extensive facial tumor involvement are presented, each having undergone wide local resection after multiple previous local excisions had failed to control the tumor and its locally deforming and destructive effects.
R F, Smith, J M, Toomey, G G, Snyder
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AbstractFacial plexiform neurofibroma is a relatively rare manifestation of Von Recklinghausen's neurofibromatosis. Two patients with extensive facial tumor involvement are presented, each having undergone wide local resection after multiple previous local excisions had failed to control the tumor and its locally deforming and destructive effects.
R F, Smith, J M, Toomey, G G, Snyder
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Solitary Plexiform Neurofibroma
Dermatologica, 2009A 35-year-old man with a solitary subcutaneous cord running on the abdomen wall is reported. Histologic examination of the lesion permitted a diagnosis of plexiform neurofibroma. In this patient and in his family no other signs of von Recklinghausen’s disease were found.
F G, Aloi, R, Massobrio
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American Journal of Medical Genetics, 1999
Plexiform neurofibromas are among the most common and debilitating complications of neurofibromatosis type 1 (NF1). They account for substantial morbidity, including disfigurement, functional impairment, and may even be life threatening. Plexiform neurofibromas are also subject to transformation into malignant peripheral nerve sheath tumor (MPNST), a ...
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Plexiform neurofibromas are among the most common and debilitating complications of neurofibromatosis type 1 (NF1). They account for substantial morbidity, including disfigurement, functional impairment, and may even be life threatening. Plexiform neurofibromas are also subject to transformation into malignant peripheral nerve sheath tumor (MPNST), a ...
openaire +2 more sources
Plexiform neurofibromas in childhood
Journal of Pediatric Surgery, 1972Abstract Sixteen cases of plexiform neurofibroma occurring in childhood have been discussed. Of lesions in the trunk or extremities, only two required multiple procedures, including a below-the-knee amputation. All patients are free of tumor at present, though they carry other stigmata of Von Recklinghausen's disease.
J, Raffensperger, R, Cohen
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Journal of Clinical Oncology
PURPOSE Pharmacologic therapies for neurofibromatosis type 1-associated plexiform neurofibromas (NF1-PNs) are limited; currently, none are US Food and Drug Administration–approved for adults.
C. Moertel +88 more
semanticscholar +1 more source
PURPOSE Pharmacologic therapies for neurofibromatosis type 1-associated plexiform neurofibromas (NF1-PNs) are limited; currently, none are US Food and Drug Administration–approved for adults.
C. Moertel +88 more
semanticscholar +1 more source