Results 71 to 80 of about 29,620 (204)

Bilateral Giant Plexiform Neurofibromas In Neurofibromatosis Type 1

Indian Journal of Dermatology, 2002
A single plexiform neurofibroma or two of any type are considered diagnostic of neurofibromatosis type 1 (NF). Plexiform neurofibromas are congenital and pathognomonic for NF-1.
Thappa D . M, Jeevankumar B, Karthikeyan K   +2 more
doaj  

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, Volume 183, Issue 9, Page 1779-1813, May 2026.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, Volume 16, Issue 4, Page 803-813, April 2026.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Facial plexiform neurofibroma in a child with neurofibromatosis type I: A case report

Journal of Indian Society of Pedodontics and Preventive Dentistry, 2007
Plexiform neurofibroma is a non-circumscribed, thick, and irregular benign tumor of the peripheral nerve sheath. It is a virtually pathognomonic and often disabling feature of neurofibromatosis type I.
Patil K, Mahima V, Shetty S, Lahari K
doaj  

Metabolic Alterations in Macrophage Subtypes Propel Immune and Stromal Remodeling in Neurofibroma's Malignant Progression

MedComm, Volume 7, Issue 4, April 2026.
Illustration of the microenvironment factors driving malignant progression in MPNSTs. ABSTRACT Neurofibromatosis type 1 (NF1) is characterized by the development of benign plexiform neurofibromas (PNFs). In 10%–15% of patients, these tumors undergo malignant transformation into aggressive malignant peripheral nerve sheath tumors (MPNSTs).
Ling‐Ling Ge, Yue‐Hua Li, Xuan Yu, Ming‐Yan Xing, Yi‐Hui Gu, Wei Wang, Jing‐Xuan Huang, Jun Liu, Hai‐Bing Zhang, Cheng‐Jiang Wei, Zhi‐Chao Wang, Qing‐Feng Li   +11 more
wiley   +1 more source

Cardiac overload resolved by resection of a large plexiform neurofibroma on both the buttocks and upper posterior thighs in a patient with neurofibromatosis type I: a case report

BMC Surgery, 2020
Background A large plexiform neurofibroma in patients with neurofibromatosis type I can be life threatening due to possible massive bleeding within the lesion.
Taro Mikami, Yuki Honma-Koretsune, Yui Tsunoda, Shintaro Kagimoto, Yuichiro Yabuki, Jiro Maegawa, Takashi Terauchi, Shintaro Nawata, Hiroyuki Kamide, Yoshinobu Ishiwata, Tabito Kino, Teruyasu Sugano   +11 more
doaj   +1 more source

Plexiform neurofibromas of the brachial plexuses [PDF]

Neurology, 2005
A 47-year-old woman was admitted to our Neurology Department with a 13-year history of slowly progressing atrophy and weakness of the upper extremities, and numerous masses in the supraclavicular regions. MRI examination (figure) revealed plexiform neurofibromas of …
Boguslaw, Paradowski, Malgorzata, Bilinska, Marek, Sasiadek, Michal, Jelen   +3 more
openaire   +2 more sources

Solitary Nodule in the Hard Palate

Oral Diseases, EarlyView.
Sara Lia Gonçalves de Lima, Poliana Soares Cruz, Maria Gabriela Candido Dias, Láysa Tavares de Melo, Laura Maria dos Santos Reis Rocha de Castro, Felipe Paiva Fonseca, Brunno Santos de Freitas Silva   +6 more
wiley   +1 more source

Multidimensional ultrasound and computed tomography imaging support in bleeding plexiform neurofibromatosis of the scalp: A case report and literature review

Indian Journal of Dermatology, 2015
Active bleeding in plexiform neurofibromatosis can be a life-threatening complication in neurofibromatosis type 1 (NF1). The prompt imaging support of 2D-3D ultrasound (US) and computed tomography (CT) during the active hemorrhage phase of cutaneous ...
Ximena Wortsman, Nelson Lobos, Rodrigo De la Parra, Laura Carreno   +3 more
doaj   +1 more source

Lateral Cutaneous Branch of the Intercostal Nerve as a Donor Site for Nerve Reconstruction Following Enucleation of an Upper Extremity Schwannoma

Clinical Case Reports, Volume 14, Issue 3, March 2026.
Fascicular defect after median nerve schwannoma enucleation reconstructed with a graft from the lateral cutaneous branch of the intercostal nerve. ABSTRACT The lateral cutaneous branch of the intercostal nerve is a reliable donor for upper extremity nerve reconstruction after schwannoma enucleation, offering easy anatomical access and potential for ...
Erika Koyama, Yoshinori Suzuki, Shuji Yamashita   +2 more
wiley   +1 more source