Results 91 to 100 of about 90,317 (313)

Development and Characterization of PLGA Nanoparticle-Laden Hydrogels for Sustained Ocular Delivery of Norfloxacin in the Treatment of Pseudomonas Keratitis: An Experimental Study

Drug Design, Development and Therapy, 2021
Rana M Gebreel,1 Noha A Edris,2 Hala M Elmofty,2 Mina I Tadros,3,4 Mohamed A El-Nabarawi,3 Doaa H Hassan1 1Department of Pharmaceutics, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, Giza, Egypt ...
Gebreel RM, Edris NA, Elmofty HM, Tadros MI, El-Nabarawi MA, Hassan DH   +5 more
doaj  

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Uniform-sized insulin-loaded PLGA microspheres for improved early-stage peri-implant bone regeneration

Drug Delivery, 2019
Poor initial stability at the first four weeks after surgery is becoming the major causes for metal implant failure. Previous attempts neglected the control release of insulin for the bone regeneration among nondiabetic subjects. The major reason may lie
Xing Wang, Feng Qi, Helin Xing, Xiaoxuan Zhang, Chunxiang Lu, Jiajia Zheng, Xiuyun Ren   +6 more
doaj   +1 more source

Graphenic materials for biomedical applications [PDF]

, 2019
Graphene-based nanomaterials have been intensively studied for their properties, modifications, and application potential. Biomedical applications are one of the main directions of research in this field. This review summarizes the research results which
Jampílek, Josef, Plachá, Daniela
core   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Crucial Role of PLGA Nanoparticles in Mitigating the Amiodarone-Induced Pulmonary Toxicity

International Journal of Nanomedicine, 2021
Amira Motawea,1 Dalia Alsaied Moustafa Ahmed,2 Ahmed A El-Mansy,3,4 Noha Mohamed Saleh1 1Pharmaceutics Department, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt; 2Forensic Medicine and Clinical Toxicology Department, Faculty of Medicine ...
Motawea A, Ahmed DAM, El-Mansy AA, Saleh NM   +3 more
doaj  

Development of a targeted and controlled nanoparticle delivery system for FoxO1 inhibitors [PDF]

, 2020
Background: Poly (lactic-co-glycolic acid) (PLGA) and polyethylene glycol (PEG) are polymers approved by the United States’ Food and Drug Administration.
Cheng, Zhiyong, Ferrer Vega, Andrea, Imondo, Michael, Lewinski, Nastassja, McInnes, Bridget T., Mulyar, Andriy   +5 more
core   +1 more source

Performance of mesenchymal cell-scaffold constructs in human oral reconstructive surgery: a systematic review [PDF]

, 2016
Background: Different sources of cultured cells combined with different scaffolds (allogenic, xenogeneic, alloplastic or composite materials) have been tested extensively in vitro and in preclinical animal studies, but there have been only a few ...
ANNIBALI, Susanna, Cristalli, Maria Paola, LA MONACA, Gerardo, MARINI, ROBERTA, Patini, Romeo, PRANNO, NICOLA   +5 more
core   +1 more source

Development of Risperidone PLGA Microspheres

Journal of Drug Delivery, 2014
The aim of this study was to design and evaluate biodegradable PLGA microspheres for sustained delivery of Risperidone, with an eventual goal of avoiding combination therapy for the treatment of schizophrenia. Two PLGA copolymers (50 : 50 and 75 : 25) were used to prepare four microsphere formulations of Risperidone. The microspheres were characterized
Susan D'Souza, Jabar Faraj, GIOVAGNOLI, Stefano, Patrick DeLuca   +3 more
openaire   +2 more sources

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source