Results 81 to 90 of about 90,317 (313)

Lysozyme Release and Polymer Erosion Behavior of Injectable Implants Prepared from PLGA-PEG Block Copolymers and PLGA/PLGA-PEG Blends [PDF]

open access: yesPharmaceutical Research, 2013
We evaluated the controlled release of lysozyme from various poly(D,L-lactic-co-glycolic acid) (PLGA) 50/50-polyethylene glycol (PEG) block copolymers relative to PLGA 50/50.Lysozyme was encapsulated in cylindrical implants (0.8 mm diameter) by a solvent extrusion method. Release studies were conducted in phosphate buffered saline +0.02% Tween 80 (PBST)
Vesna Milacic, Vesna Milacic   +1 more
openaire   +2 more sources

Sprayable Polymer Blends With Short‐Chain Surface Segregation for Preventing Postoperative Abdominal Adhesions

open access: yesAdvanced Healthcare Materials, EarlyView.
Adhesions’ high occurrence rates and high morbidity render them a critical challenge to be addressed. Current prevention methods, such as physical barriers, have many limitations, resulting in inconsistent safety and efficacy. This study demonstrates the potential for sprayable polymeric materials as an adhesion barrier.
Robert J. Morris III   +7 more
wiley   +1 more source

Design and Optimization of Sustained-Release Dental Implants for Targeted Periodontal Drug Delivery

open access: yesJournal of Pharmacy and Bioallied Sciences
Background: Periodontal therapy often requires sustained and targeted drug delivery to enhance therapeutic outcomes and minimize systemic side effects.
Silpi Chatterjee   +5 more
doaj   +1 more source

Soft and Hard Implant Fabrication Using 3D-Bioplotting TM [PDF]

open access: yes, 2004
At the Freiburger Materialforschungszentrum we have developed a new process (3DBioplotting TM) that permits most kind of polymers and biopolymers to be used in 3D scaffold design, including hydrogels (e.g. collagen, agar), polymer melts (e.g. PLLA, PGA,
Carvalho, C., Landers, R., Mülhaupt, R.
core   +1 more source

MiR-219a-5p Enriched Extracellular Vesicles Induce OPC Differentiation and EAE Improvement More Efficiently Than Liposomes and Polymeric Nanoparticles [PDF]

open access: yes, 2020
Remyelination is a key aspect in multiple sclerosis pathology and a special effort is being made to promote it. However, there is still no available treatment to regenerate myelin and several strategies are being scrutinized.
Alberro, Ainhoa   +17 more
core   +3 more sources

Wound Geometry Determines Whether Aligned‐Fiber Scaffolds Accelerate or Impede Diabetic Wound Healing: A Biased Random Walk Analysis

open access: yesAdvanced Healthcare Materials, EarlyView.
Wound closure is governed by geometry‐orientation coupling: aligned fibers speed migration along their axis but hinder perpendicular advance. In vivo diabetic wound experiments with composition‐matched fibrin, combined with an anisotropic diffusion (biased random‐walk) model, quantify this trade‐off and generate a healing landscape.
Yin‐Yuan Huang   +13 more
wiley   +1 more source

Biocompatible PLGA-Mesoporous Silicon Microspheres for the Controlled Release of BMP-2 for Bone Augmentation

open access: yesPharmaceutics, 2020
Bone morphogenetic protein-2 (BMP-2) has been demonstrated to be one of the most vital osteogenic factors for bone augmentation. However, its uncontrolled administration has been associated with catastrophic side effects, which compromised its clinical ...
Silvia Minardi   +7 more
doaj   +1 more source

Electrospray synthesis of PLGA TIPS microspheres [PDF]

open access: yes, 2015
We successfully demonstrate the synthesis of polymer microspheres using a single electrospray source, and show their physical characterisation. Electrospray has proven to be a versatile method to manufacture particles, giving tight control over size with
Bowen, J.   +6 more
core  

Unbreakable codes in electrospun fibers : digitally encoded polymers to stop medicine counterfeiting [PDF]

open access: yes, 2010
Fluorescent polymer solutions can easily be electrospun into micrometer-sized fibers and subsequently encoded with long lasting digital codes by a photobleaching process.
Braeckmans, Kevin   +9 more
core   +2 more sources

A New 3D Colon on a Chip to Decipher the Influence of Mechanical Forces on the Physiological Cellular Ecosystem

open access: yesAdvanced Healthcare Materials, EarlyView.
To dissect how mechanical forces influence intestinal physiology, we developed a stretchable 3D colon‐on‐chip that integrates tunable topography, stiffness and peristalsis‐like motion within a physiologically relevant microenvironment. We showed that stretching is a dominant factor governing epithelial behavior, markedly enhancing proliferation and ...
Moencopi Bernheim‐Dennery   +10 more
wiley   +1 more source

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