PLGA nanofibers carrying rhFGF1 for the effective treatment of skin wounds in diabetic mice. [PDF]
Zhang Y +6 more
europepmc +1 more source
Corrigendum: Effect of PLGA block molecular weight on gelling temperature of PLGA‐PEG‐PLGA thermoresponsive copolymers [PDF]
openaire +1 more source
Biodegradable Natural Polymer‐Based Drug Delivery Systems for Bone Tissue Engineering
ABSTRACT The increasing incidence of bone diseases and injuries, especially among aging populations, has underscored the shortcomings of traditional treatments such as bone grafts and metal implants, which often face complications including immune rejection, mechanical failure, and delayed healing.
Hyejin Jo +4 more
wiley +1 more source
Ultrasound-guided nanocomposite hydrogel injection to enhance nerve repair via temporal delivery of a colony-stimulating factor 1 receptor inhibitor. [PDF]
He Z +8 more
europepmc +1 more source
Mengdi Wang,1,* Shan Wang,1,* Changhao Zhang,2,* Ming Ma,1 Bohua Yan,1 Xinming Hu,2 Tianjiao Shao,2 Yan Piao,2 Lili Jin,2 Jing Gao1 1State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and ...
Wang M +9 more
doaj
Integrating ML and multi‐objective optimization enabled efficient, accurate design of nanocarriers with optimized loading and encapsulation efficiencies. ABSTRACT Oxaliplatin (OXA), a critical third‐generation platinum chemotherapeutic, is significantly limited by suboptimal loading capacity and encapsulation efficiency in nanoparticle‐based delivery ...
Abbas Rahdar +3 more
wiley +1 more source
Nanocomposite hydrogel acupoint therapy for sustained pregabalin delivery and long-term neuropathic pain relief. [PDF]
Duan X +8 more
europepmc +1 more source
Machine Learning Assisted Prediction of Degradation Behavior of Poly(Lactic‐Co‐Glycolic Acid)
Using a gradient boosting‐based machine learning model trained on 484 data points, this study predicts the degradation behavior of poly(lactic‐co‐glycolic acid) (PLGA) implants. Degradation time, molecular weight, and lactide/glycolide ratio were identified as key governing factors, enabling accurate prediction while reducing reliance on extensive ...
Shuai Wang +11 more
wiley +1 more source
Dual-Action Theranostic Nanoparticles Delivering Toll-Like Receptor 2 Inhibitors and Chemotherapy Target Breast Cancer Cells and the Tumor Microenvironment. [PDF]
Di Lorenzo A +11 more
europepmc +1 more source
ABSTRACT Primary brain tumors are life‐threatening diseases. Glioblastoma is the most aggressive type with a poor prognosis. Medulloblastoma is the most common pediatric brain tumor. While surgical treatments often result in recurrences owing to the complex nature of the tumor microenvironment, conventional treatments lower the quality of life of ...
Ilkay Irem Ozbek +3 more
wiley +1 more source

