Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Evaluation of pressure parameters intra-abdominal and thoracic in patients submitted to abdominoplasty [PDF]
INTRODUCTION: The abdomen is an important aesthetic and functional segment in the characterization of body contouring. The plication of the rectus abdominis may cause various problems to the patient such as increased intra-abdominal and thoracic pressure.
Jefferson di Lamartine Galdino Amaral +7 more
doaj +1 more source
An infra-red finger tracking system used in the assessment and remediation of “graph-as-picture” misconceptions [PDF]
The workshop presentation will describe a specialized ap- plication of Lee’s “Wiimote Whiteboard” [7] an infra-red camera based tracking system which uses the Nintendo Wii wireless remote control unit and Bluetooth. Young students wear a very small infra-
Cox, Richard, Garcia Garcia, Grecia
core
Posterior Plication or Combined Plication of the Recti Diastasis
AbstractThe anterior abdominal wall consists of the abdominal rectus muscles separated by the linea alba, which is the fusion of the aponeuroses of external and internal oblique muscles and transversus abdominis.
Davide Lomanto +2 more
openaire +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Medial rectus resection versus plication in basic type intermittent exotropia
Purpose To compare the efficacy of unilateral recession-resection (RR) versus unilateral recession-plication (RP) in basic-type intermittent exotropia (X (T)).
Hanan S. Hegazy, Mona N. Mansour
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Secondary diaphragmatic eventration after resection of extralobar pulmonary sequestration
Phrenic nerve preservation is an important factor in operations involving the resection of an extralobar pulmonary sequestration. We present a case of secondary diaphragmatic eventration due to damage to the phrenic nerve after resection of an extralobar
Kaselas C +3 more
doaj
A “near miss" congenital eventration of the right hemidiaphragm in a neonate: a case report [PDF]
Focal eventration involving the posterior segment of the hemidiaphragm is a rare congenital anomaly. We report of a 10-day-old infant who presented with significant respiratory insufficiency and failure to show any responses to standard treatment.
Bahari @ Mohd Fakhruddin, Mughni +4 more
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source

