Results 41 to 50 of about 32,806 (255)

Ploidy and the Causes of Genomic Evolution [PDF]

Journal of Heredity, 2009
Genomes vary dramatically in size and in content. This variation is driven in part by numerous polyploidization events that have happened over the course of eukaryotic evolution. Experimental evolution studies, primarily using the yeast Saccharomyces cerevisiae, provide insights into the immediate fitness effects of ploidy mutations, the ability of ...
Aleeza C, Gerstein, Sarah P, Otto
openaire   +2 more sources

Introgressed Variation in TaMYB7‐A1 Drives Graded Dormancy and Climate‐Adaptive Pre‐Harvest Sprouting Resistance in Wheat

Advanced Science, EarlyView.
TaMYB7‐A1 directly activates TaABI5 to enhance ABA signaling and regulate ABA‐GA homeostasis, enforcing seed dormancy. Its superior allele, derived from wild einkorn introgression, harbors a MITE insertion that elevates expression and two amino acid substitutions that enhance transcriptional activity, collectively generating graded PHS resistance for ...
Hao Wang, Dongzhi Wang, Yafei Guo, Qi Zheng, Min Zhang, James Simmonds, Jian Hou, Xuemei Liu, Xuelei Lin, Xiaomin Bie, Xiansheng Zhang, Xiaohui Li, Yuan Chen, Xueyong Zhang, Cristobal Uauy, Fei Lu, Chengcai Chu, Zhixi Tian, Jun Xiao   +18 more
wiley   +1 more source

Identification of Paternal Uniparental Disomy on Chromosome 22 and a De-novo Deletion on Chromosome 18 in Individuals with Orofacial Clefts [PDF]

, 2018
Background: Orofacial clefts are the most common malformations of the head and neck region. Genetic and environmental factors have been implicated in the etiology of these traits.Methods: We recently conducted genotyping of individuals from the African ...
Abate, Firke, Abdur-Rahman, Lukman Olajide, Adeyemo, Adebowale, Adeyemo, Wasiu L., Aregbesola, Babatunde S., Audu, Rosemary, Bello, Saidu A., Busch, Tamara D., Butali, Azeez, Donkor, Peter, Eshete, Mekonen A., Gowans, Lord J. J., Halilu, Taiye, Jain, Deepti, Laurie, Cathy C., Laurie, Cecelia A., Marazita, Mary L., Mossey, Peter, Murray, Jeffrey C., Obiri-Yeboah, Solomon, Oginni, Fadekemi, Ogunlewe, Olugbenga M., Oladugba, Abimbola V ., Olaitan, Peter Babatunde, Olutayo, James, Onwuamah, Chika K., Oseni, Ganiyu O., Owais, Arwa, Plange-Rhule, Gyikua   +28 more
core   +2 more sources

Scaling of cellular proteome with ploidy

bioRxiv, 2021
Ploidy changes are frequent in nature and contribute to evolution, functional specialization and tumorigenesis (1,2). Analysis of model organisms of different ploidies revealed that increased ploidy leads to an increase in cell and nuclear volume ...
G. Yahya, P. Menges, D. A. Ngandiri, Daniel Schulz, A. Wallek, N. Kulak, M. Mann, P. Cramer, V. Savage, Markus Raeschle, Z. Storchová   +10 more
semanticscholar   +1 more source

Linking Plant Metabolomics with Fungal Functional Dynamics Reveals a Noncanonical S‐R‐C Adaptive Trajectory

Advanced Science, EarlyView.
Using field‐based holo‐omics, we demonstrate that developmental shifts in sorghum leaf metabolomes drive a noncanonical fungal succession from stress tolerators (S) through ruderals (R) to competitors (C). Antifungal metabolites in young leaves select for S strategists with expanded genomes, transient maltose pulses during flowering favor fast‐growing ...
Peilin Chen, John W. Taylor, Cheng Gao
wiley   +1 more source

Recombining your way out of trouble: the genetic architecture of hybrid fitness under environmental stress [PDF]

, 2020
Hybridization between species is a fundamental evolutionary force that can both promote and delay adaptation. There is a deficit in our understanding of the genetic basis of hybrid fitness, especially in non-domesticated organisms.
Bendixsen, D., Greig, D., Janzen, T., Nolte, A., Stelkens, R., Zhang, Z.   +5 more
core   +1 more source

Increased dietary phosphorous prevents vertebral deformities in triploid Atlantic salmon (Salmo salar L.)

, 2016
Triplicate groups of triploid and diploid Atlantic salmon were fed diets with a low (LP, total P: 7.1 g kg−1), medium (MP, total P: 9.4 g kg−1) or high (HP, total P: 16.3 g kg−1) phosphorous (P) level from first feeding (0.18 g) to transfer to sea water (
P. Fjelldal, T. Hansen, E. Lock, A. Wargelius, T. W. Fraser, F. Sambraus, A. El-Mowafi, S. Albrektsen, R. Waagbø, R. Ørnsrud   +9 more
semanticscholar   +1 more source

Water temperature and dietary histidine affect cataract formation in Atlantic salmon (Salmo salar L.) diploid and triploid yearling smolt.

Journal of Fish Diseases, 2017
The aim of the present study was to investigate cataract development in diploid (2N) and triploid (3N) Atlantic salmon smolts and post-smolts at two water temperatures (10 and 16 °C) given diets with different histidine supplementation (LH, 10.4 and HH ...
F. Sambraus, P. Fjelldal, S. Remø, E. Hevrøy, T. Nilsen, A. Thorsen, T. Hansen, R. Waagbø   +7 more
semanticscholar   +1 more source

PIEZO1 is Required for Acute Myeloid Leukemia Progression and Leukemia Stem Cell Maintenance via HIF1A‐SLC7A11 Axis‐Mediated Ferroptosis Defense

Advanced Science, EarlyView.
This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang, Ziyan Cao, Kexin Gao, Shuxin Yao, Yanbing Zheng, Manman Cui, Rong Yin, Guoqiang Han, Jin Hu, Chengyi Wang, Haojian Zhang   +10 more
wiley   +1 more source

Chromosome-breakage genomic instability and chromothripsis in breast cancer [PDF]

, 2014
Background: Chromosomal breakage followed by faulty DNA repair leads to gene amplifications and deletions in cancers. However, the mere assessment of the extent of genomic changes, amplifications and deletions may reduce the complexity of genomic data ...
Barrett, Michael T, Basik, Mark, Greenwood, Celia MT, Klein, Kathleen, Lenkiewicz, Elizabeth, Nabavi, Sheida, Przybytkowski, Ewa   +6 more
core   +1 more source