Results 61 to 70 of about 10,555 (279)

Squamate ventricular cardiomyocytes: Ploidy, proliferation, and heart muscle cell size in the leopard gecko (Eublepharis macularius)

Developmental Dynamics, EarlyView.
Abstract Background While heart function is broadly conserved across vertebrates, the cellular phenotype of muscle cells (cardiomyocytes) varies across taxa and throughout ontogeny. Emerging evidence suggests that some attributes may correlate with the capacity for spontaneous cardiomyocyte replacement following injury.
Kathy Jacyniak, Karemna Barrera Jaimes, Minh Hanh Doan, Jordyn M. Chartrand, Matthew K. Vickaryous   +4 more
wiley   +1 more source

Surviving the Storm: The Role of Poly‐ and Depolyploidization in Tissues and Tumors

Advanced Science
Polyploidization and depolyploidization are critical processes in the normal development and tissue homeostasis of diploid organisms. Recent investigations have revealed that polyaneuploid cancer cells (PACCs) exploit this ploidy variation as a survival ...
Yucui Zhao, Sijia He, Minghui Zhao, Qian Huang   +3 more
doaj   +1 more source

Red rot disease resistance in interspecific hybrids of sugarcane derived from diverse cytotypes of Saccharum spontaneum L.

Journal of Sugarcane Research
Red rot disease has caused major loss to sugarcane crops for more than a hundred years.  It  is caused by the fungal pathogen Colletotrichum falcatum Went.
ANGANNAN SUGANYA, P. Govindaraj, A.Selvi, Viswanathan R   +3 more
doaj   +1 more source

The chromosome number and heterochromatin distribution pattern suggest differentiation among species of the Stylosanthes scabra-seabrana complex [PDF]

Anais da Academia Brasileira de Ciências
The genus Stylosanthes has economic importance in semi-arid regions and requires studies that reveal complex relationships between species involving different ploidies.
IRLANE CRISTINE S.A. LIRA, NATONIEL F. DE MELO, RAFAELA PRISCILA ANTONIO, RONALDO S. DE OLIVEIRA, MANOEL A. DE QUEIROZ   +4 more
doaj   +1 more source

Loss of the Y Chromosome in Oral Potentially Premalignant Disorders Predicts Malignant Progression: An Integrative Cross‐Species Multi‐Cohort Bioinformatic Study

Head &Neck, EarlyView.
ABSTRACT Background The loss of the Y chromosome (LOY) and the extreme down‐regulation of Y chromosome gene expression (EDY) are frequently observed in oral squamous cell carcinoma (OSCC). However, their roles in oral potentially malignant disorders (OPMDs) are unclear.
Rui Han, Jos B. Poell, Cristina Conde‐Lopez, Tuula Salo, Ina Kurth, Ruud H. Brakenhoff, Jochen Hess   +6 more
wiley   +1 more source

Malignant Transformation of Oral Leukoplakia and Proliferative Verrucous Leukoplakia and Its Biomarker Predictors: A Systematic Umbrella Review

Head &Neck, EarlyView.
ABSTRACT Background Oral leukoplakia (OL) represents the most common oral potentially malignant disorder globally, with highly variable reported malignant transformation (MT) rates creating challenges for evidence‐based clinical management. Objective To systematically synthesize evidence on MT prevalence in OL and evaluate potential predictive ...
Mohammed Taib Fatih, Mohammed Khalid Mahmood, Balkees Taha Garib, Yad Mariwan Mohammed Amin, Ranjdar Mahmood Talabani, Tara Ali Rasheed, Handren Ameer Kurda, Balen Hamid Qadir, Zana Fuad Noori, Mohammed Aso Abdulghafor, Ariwan Othman Saeed, Herve Tassery, Delphine Tardivo, Romain Lan   +13 more
wiley   +1 more source

Variance of ploidy in Candida albicans [PDF]

Journal of Bacteriology, 1982
Determination of ploidy was performed on isolates of Candida albicans from clinical sources by measuring nuclear DNA content with fluorescent microscope photometry. By this criterion and UV irradiation survival experiments, haploid, diploid, and tetraploid strains were identified in this organism.
Takahito Suzuki, K Tanaka, S Nishibayashi, T Kuroiwa, T Kanbe   +4 more
openaire   +3 more sources

New cell lines expanding the diversity of Ewing sarcoma models

International Journal of Cancer, EarlyView.
What's New? A chromosomal translocation between the EWSR1 and ETS genes is the key oncogenic driver in Ewing sarcoma. EWSR1::FLI1, the most frequent fusion, is subdivided into different fusion types with unclear prognostic relevance. Here, the authors describe the establishment and characterization of four new, intrinsically immortal, patient‐derived ...
Maximilian Kerkhoff, Christiane Schaefer, Wilhelm G. Dirks, Dawid Krzeciesa, Maximilian Bretschneider, Pauline R. Plaumann, Wiebke K. Guder, Arne Streitbürger, Sonja Herter, Heike Peterziel, Ina Oehme, Felina Zahnow, Thomas G. P. Grünewald, Uta Dirksen   +13 more
wiley   +1 more source

Triploidy in the hematology of jundia juveniles (Siluriformes: Heptapteridae)

Brazilian Journal of Biology
This study compared the hematological characteristics of diploid and triploid of jundia, Rhamdia quelen juveniles, an important freshwater fish cultured in south Brazil.
H Fukushima, RL Bailone, LA Weiss, ML Martins, E Zaniboni-Filho   +4 more
doaj   +1 more source

Olaparib for patients with tumors harboring alterations in homologous recombination repair genes: Results from the drug rediscovery protocol

International Journal of Cancer, EarlyView.
What's New? PARP inhibitors are effective in patients with inactivating alterations in the BRCA1/2 genes across tumor types. However, the efficacy of PARP inhibitors in patients with other inactivated homologous recombination repair genes remains unclear. This knowledge gap and discrepancies in EMA/FDA approvals highlight the need for better biomarkers.
Ilse A. C. Spiekman, Niven Mehra, Laurien J. Zeverijn, Birgit S. Geurts, Karlijn Verkerk, Soemeya F. Haj Mohammad, Vincent van der Noort, Paul Roepman, Wendy W. J. de Leng, Anne M. L. Jansen, Addy C. M. van de Luijtgaarden, Theo van Voorthuizen, Tineke E. Buffart, Hans Gelderblom, Emile E. Voest, Henk M. W. Verheul   +15 more
wiley   +1 more source