Results 61 to 70 of about 4,591 (253)
Efficient Generation of Megakaryocyte Progenitors and Platelets From HSPCs via JAK2/STAT3 Signaling
Advanced Science, EarlyView.This research presents a novel strategy employing the VGM cocktail, which combines HES7 overexpression with HDAC inhibitor and GABA, to enhance platelet production from hematopoietic stem and progenitor cells by promoting megakaryocyte progenitor (MkP) generation.
Huicong Liu +6 more
wiley +1 more source
Scientific Reports, 2021 Bananas are vital for food security in many countries, and half of banana production relies solely on ‘Cavendish’ (AAA), which is presently threatened by the fungal pathogen Fusarium oxysporum f. sp. cubense (Foc) tropical race 4.
R. Thangavelu +9 more
doaj +1 more source
Control of Transcription by Cell Size [PDF]
, 2010 Cell size increases significantly with increasing ploidy. Differences in cell size and ploidy are associated with alterations in gene expression, although no direct connection has been made between cell size and transcription.
A Mortazavi +48 more
core +4 more sources
Advanced Science, EarlyView.The waterlogging tolerance of allotetraploid Actinidia valvata is inherited from one of its diploid progenitors, which leads to subgenome expression dominance, mediated by complex mechanisms including altered chromatin accessibility and DNA methylation.
Xiaoli Hu +14 more
wiley +1 more source
Ploidy influences on metabolic substrate deposition of rainbow trout
Acta Scientiarum: Animal Sciences, 2019 Triploid fish are usually sterile. Thus, the energy and nutrients intended for sexual maturation may be available to enhance flesh quality and physical growth.
Aline Dal`Olio Gomes +5 more
doaj +1 more source
The Plant Genome, 2023 Sugarcane has a complex, highly polyploid genome with multi‐species ancestry. Additive models for genomic prediction of clonal performance might not capture interactions between genes and alleles from different ploidies and ancestral species.
Chensong Chen +8 more
doaj +1 more source
American Journal of Botany, EarlyView.Abstract Premise Species complexes are groups of closely related species with ambiguous delimitation, often composed of recently diverged lineages. Polyploidization and uniparental reproduction (i.e., selfing and apomixis) can play important roles in the origin of species complexes. These complexes pose challenges for species‐based scientific questions,
Anne‐Sophie Quatela +7 more
wiley +1 more source
Cellular changes during Medicago truncatula hypocotyl growth depend on temperature and genotype. [PDF]
, 2014 Hypocotyl growth is a key characteristic for plant emergence, influenced by environmental conditions, particularly temperature, and varying among genotypes.
B. Teulat +5 more
core +3 more sources
Ploidy and the Causes of Genomic Evolution [PDF]
Journal of Heredity, 2009 Genomes vary dramatically in size and in content. This variation is driven in part by numerous polyploidization events that have happened over the course of eukaryotic evolution. Experimental evolution studies, primarily using the yeast Saccharomyces cerevisiae, provide insights into the immediate fitness effects of ploidy mutations, the ability of ...
Aleeza C. Gerstein, Sarah P. Otto
openaire +3 more sources
American Journal of Hematology, EarlyView.ABSTRACT We analyzed 193 Fanconi anemia patients from the Italian Registry, focusing on hematological outcome, cancer risk, and mortality, both in transplanted (n = 130, 67.4% of the cohort) and non‐transplanted (n = 63, 36.6% of the cohort) patients. After a median follow‐up of 7 years, almost all patients developed cytopenia that was more frequent in
Erica Ricci +35 more
wiley +1 more source