Results 271 to 280 of about 88,719 (358)

Heterogeneity Landscape of Circulating Tumor Cells in Clinical Utility

Advanced Therapeutics, Volume 8, Issue 10, October 2025.
This study reports the heterogeneity spectrum of circulating tumor cells. The factors involved in the spectrum promote CTCs to overcome barriers in the metastatic cascade but impact the clinical outcome of cancer patients. In summary, the heterogeneities in association with CTCs ultimately reduce patient survival and facilitate increasing mortality of ...
Md Kowsar Alam, Lu Yanjun, Bee Luan Khoo, Tongxu Si, Heng Zou, Mengsu Yang   +5 more
wiley   +1 more source

Tendency towards clonality: deviations of meiosis in parthenogenetic Caucasian rock lizards†. [PDF]

Biol Reprod
Spangenberg V, Arakelyan M, Simanovsky SA, Dombrovskaya Y, Khachatrian ER, Kolomiets O.   +5 more
europepmc   +1 more source

Tumor vascularization, mitotic index, histopathologic grade, and DNA ploidy in the assessment of 114 head and neck squamous cell carcinomas

, 1995
Jerzy Klijanienko, Filippo De Braud, Anna Russo, François Janot, B Luboïnski, Esteban Cvitkovic, Adel K. El-Naggar, José Luis Rodríguez‐­Peralto, Rosario Rodríguez, M. Itzhaki   +9 more
openalex   +1 more source

A Novel Cultivation System for Germ Cell Proliferation and Sustaining Whole Testicular Niche

Advanced Science, Volume 12, Issue 39, October 20, 2025.
A hydrogel microneedle‐based system enables whole testicular cultivation, supporting spermatogonial proliferation and enhancing spermatogenesis in vitro. This ‘whole testicular spermatogonia pool’ (WTSP) significantly increases spermatid production and fertility potential in mice. This system also promotes spermatogonial expansion in human fetal testes,
Yu Xia, Xiaoxuan Zhang, Bohang Zhang, Minhui Lu, Qing Cheng, Li Liu, Lifang Shi, Yiqiang Cui, Dingdong Chen, Laihua Li, Xuejiang Guo, Jingtao Guo, Jiahao Sha, Yuanjin Zhao, Yan Yuan   +14 more
wiley   +1 more source

Workflow for efficiently isolating microspore cultures of different rice genotypes by optimizing the callus induction medium. [PDF]

Front Plant Sci
Chen Z, Guo G, Zhang S, He T, Feng S, Liu C, Wang Y, Zhou L.   +7 more
europepmc   +1 more source

Large‐Scale Production of Transfusion‐Ready Red Blood Cells From Induced Pluripotent Stem Cells

Advanced Science, Volume 12, Issue 38, October 13, 2025.
A scalable, dynamic culture system is developed to produce red blood cells from induced pluripotent stem cells. It achieves high yields with up to 70% enucleation, not previously shown in dynamic systems, overcoming key limitations and enabling large‐scale production.
Eszter Varga, Eelke Brandsma, Brenda E. Juarez‐Garza, Renuka P. E. Ramlal, Julien J. Karrich, Adrien Laurent, Athina Chavli, Ruthmila Paskel, Kerly Fu, Richard A. Flavell, Marieke von Lindern, Derk Amsen, Marieke E. Klijn, Emile van den Akker   +13 more
wiley   +1 more source

Whole genome duplication drives transcriptome reprogramming in response to drought in alfalfa. [PDF]

Plant Cell Rep
Santoro DF, Anderson AW, Alavi SN, Malatesta Pierleoni VA, Rosellini D.   +4 more
europepmc   +1 more source

DNA ploidy heterogeneity in early and advanced gastric cancers

, 1996
Eiji Fujimaki, Kohsuke Sasaki, Osamu Nakano, Shigeki Chiba, Hideki Tazawa, H Yamashiki, Seishi Orii, Tamotsu Sugai   +7 more
openalex   +1 more source

Counting the Invisible: New Tools to Estimate the Number of Contributors From Sequence‐Based Microsatellite Genotyping of Environmental DNA Samples

Molecular Ecology Resources, Volume 25, Issue 8, November 2025.
Olivier Lepais, Ivan Paz‐Vinas
wiley   +1 more source

Patient With Prolidase Deficiency due to an Homozygous PEPD Variant, Induced by Paternal Uniparental Isodisomy of Chromosome 19

American Journal of Medical Genetics Part A, Volume 197, Issue 10, October 2025.
ABSTRACT Uniparental disomy (UPD) is a rare phenomenon in which both copies of a chromosome are inherited from a single parent. This can lead to genomic imprinting disorders and recessive disorders due to the presence of recessive pathogenic variants in both alleles. Additionally, depending on the mechanisms by which UPD occurs, mosaic aneuploidies may
Marta Carreño‐Hidalgo, Raquel Muñoz‐Siles, Vanesa López‐González, Lidia Carreño‐Gago, Lluís Armengol Dulcet   +4 more
wiley   +1 more source