Results 31 to 40 of about 35,320 (237)
Inferring Variation in Copy Number Using High Throughput Sequencing Data in R
Frontiers in Genetics, 2018 Inference of copy number variation presents a technical challenge because variant callers typically require the copy number of a genome or genomic region to be known a priori.
Brian J. Knaus, Niklaus J. Grünwald
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Do plant ploidy and pollinator tongue length interact to cause low seed yield in red clover?
Ecosphere, 2021 The loss of long‐tongued pollinator species and dominance of a few short‐tongued generalist species, related to agricultural intensification in recent decades, may have consequences for the quality, quantity, and stability of yields in insect‐pollinated ...
Veronica Hederström +5 more
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PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites
Advanced Science, EarlyView.This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang +13 more
wiley +1 more source
Ploidy determination of Canadida albicans [PDF]
Journal of Bacteriology, 1979 The dimorphic yeast Candida albicans, as a member of the fungi imperfecti, has been assumed to be in the haploid, or imperfect, state. The deoxyribonucleic acid content of this species has been measured by flow microfluorometry, a technique capable of analyzing single cells.
A F, Olaiya, S J, Sogin
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Advanced Science, EarlyView.This study reveals the mechanism by which jasmonic acid (JA) regulates lycopene synthesis under light and dark conditions. In light, JA activates SlMYC2, which suppresses SlPIF1a and promotes SlPSY1 expression. In darkness, JA induces the acetyltransferase SlNATA1, which acetylates the dark‐accumulated SlPIF1a, thereby repressing SlPSY1 expression ...
Jiayi Xu +10 more
wiley +1 more source
Cardiomyocyte Ploidy, Metabolic Reprogramming and Heart Repair
Cells, 2023 The adult heart is made up of cardiomyocytes (CMs) that maintain pump function but are unable to divide and form new myocytes in response to myocardial injury.
Andrea Elia, Sadia Mohsin, Mohsin Khan
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Advanced Science, EarlyView.This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou +17 more
wiley +1 more source
Tetraploidy‐linked sensitization to CENP‐E inhibition in human cells
Molecular Oncology, 2023 Tetraploidy is a hallmark of cancer cells, and tetraploidy‐selective cell growth suppression is a potential strategy for targeted cancer therapy. However, how tetraploid cells differ from normal diploids in their sensitivity to anti‐proliferative ...
Koya Yoshizawa +14 more
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Methods and Protocols, 2023 Flow cytometry gives a unique opportunity to analyze thousands of individual cells for multiple parameters in a course of minutes. The most commonly used flow cytometry application in plant biology is estimation of nuclear DNA content.
Maria Fomicheva, Elena Domblides
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Phylogenetic systematics of Juncaceae
American Journal of Botany, EarlyView.Abstract Premise Juncaceae has needed taxonomic revision for some time. Specifically, the genus Juncus s.l. is known to be paraphyletic because five small southern‐hemisphere genera have been shown repeatedly to be nested within it. In 2022, a new classification was proposed, based on phylogenies built from one nuclear and three plastid regions ...
Reed J. Kenny +2 more
wiley +1 more source